EDS
Ethylenediaminetetraacetic acid
anhydrous, BioUltra, ≥99% (titration)
동의어(들):
(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS 번호:
Molecular Weight:
292.24
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
39030907
UNSPSC Code:
12352116
EC Number:
200-449-4
MDL number:
Beilstein/REAXYS Number:
1716295
제품 이름
Ethylenediaminetetraacetic acid, anhydrous, BioUltra, ≥99% (titration)
InChI key
KCXVZYZYPLLWCC-UHFFFAOYSA-N
InChI
1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
SMILES string
OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
grade
anhydrous
product line
BioUltra
assay
≥99% (titration)
form
powder
reaction suitability
reagent type: chelator
pH
2.5 (23 °C, 10 g/L)
mp
250 °C (dec.) (lit.)
Quality Level
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Application
EDTA has been used:
- as a medium supplement in embryo culture using synthetic oviduct fluid culture 1 (SOFC1) medium
- in incubation of EpCAM+ cells with fluorescein isothiocyanate (FITC) conjugated antibody for cell sorting analysis
- in pre-treatment of single cell suspension of dendritic cells from spleen for cell sorting with magnetic beads
General description
Ethylenediaminetetraacetic acid (EDTA) is a substituted diamine and a versatile compound in household with industrial applications. EDTA chelates metal divalent cations like calcium, magnesium, zinc, copper, manganese by forming metal-EDTA complexes. It finds its application in cleaning products and detergent formulations. In paper and pulp industries, EDTA reduces the adverse effect of metal ions on bleaching. It functions as an antibacterial agent by removing calcium and magnesium divalent cations from the outer membrane and causes loss of lipopolysaccharide from the membrane, making the bacteria susceptible to bactericidal agents. Free EDTA has adverse effect on reproduction and development in mammals. EDTA can chelate ions from deposits that contribute to atherosclerosis, cancers and heart diseases. It can help to overcome cell membrane injury by reducing radical reactions and oxidation processes. It binds to calcium and reduces the risk of hypercalcinemia in cancer patients. Transmembrane ammonium EDTA gradient method aids in drug delivery, increasing drug retention and efficacy of therapeutics and lowers the cytotoxicity levels.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
저장 등급
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
The application of EDTA in drug delivery systems: doxorubicin liposomes loaded via NH4EDTA gradient
Song Y, et al.
International journal of nanomedicine, 9, 3611-3621 (2014)
Effect of the absence or presence of various protein supplements on further development of bovine oocytes during in vitro maturation
Ali A and Sirard M
Biology of Reproduction, 66(4), 901-905 (2002)
Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
Menges M, et al.
The Journal of Experimental Medicine, 195(1), 15-22 (2002)
The phenotypes of pluripotent human hepatic progenitors
Schmelzer E, et al.
Stem Cells, 24(8), 1852-1858 (2006)
EDTA: the chelating agent under environmental scrutiny
Oviedo C and Rodriguez J
Quimica nova, 26(6), 901-905 (2003)
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| EDSPAK001 | 04053252468704 |
| EDSPAK0A1 | 04054839323430 |
| MAB1435 | 04053252610950 |
| S8005H | 04053252908934 |
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