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Merck

RDD040

Sodium dodecyl sulfate

BioReagent, Molecular Biology, ≥98.5% (GC), free-flowing, Redi-Dri

동의어(들):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
CH3(CH2)11OSO3Na
CAS 번호:
Molecular Weight:
288.38
NACRES:
NA.25
UNSPSC Code:
12161900
Beilstein/REAXYS Number:
3599286
MDL number:
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grade

Molecular Biology

Quality Level

description

anionic

product line

BioReagent, Redi-Dri

assay

≥98.5% (GC)

quality

free-flowing

mol wt

micellar 18,000

aggregation number

62

technique(s)

electrophoresis: suitable

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

anion traces

chloride (Cl-): ≤500 ppm, phosphate (PO43-): ≤10 ppm

cation traces

heavy metals (as Pb): ≤10 ppm

absorption

≤0.1 at 260 at 3%, ≤0.1 at 280 at 3%

HLB

40

suitability

suitable for electrophoresis

foreign activity

DNase, RNase, none detected

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

General description

Sodium dodecyl sulfate (SDS) is an amphipathic detergent commonly used for denaturing proteins. SDS has a long-chain aliphatic group, with negatively charged sulfate groups that coat the surface of proteins, causing them to lose their quaternary structure.

Application

Anionic detergent
Sodium dodecyl sulfate has been used:
  • in chromatin immunoprecipitation
  • in SDS-polyacrylamide gel electrophoresis (SDS-PAGE)
  • as a component of radioimmunoprecipitation assay buffer for immunoblotting

Analysis Note

Tested for use in denatured polyacrylamide gel electrophoresis.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

저장 등급

4.1B - Flammable solid hazardous materials

wgk

WGK 2

flash_point_f

338.0 °F

flash_point_c

170 °C



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시험 성적서(COA)

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문서

Redi-Dri™ prevents hygroscopic powders, such as inorganic salts, from absorbing moisture and forming clumps, leaving the salts free-flowing every time.


Kazuya Ishikawa et al.
Nature communications, 5, 5430-5430 (2014-11-13)
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Cancer research, 75(20), 4351-4363 (2015-08-25)
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S Bavamian et al.
Molecular psychiatry, 20(5), 573-584 (2015-01-28)
Bipolar disorder (BD) is a heritable neuropsychiatric disorder with largely unknown pathogenesis. Given their prominent role in brain function and disease, we hypothesized that microRNAs (miRNAs) might be of importance for BD. Here we show that levels of miR-34a, which