C7352
L-Cysteine
from non-animal source, BioReagent, suitable for cell culture, ≥98%
동의어(들):
(R)-2-Amino-3-mercaptopropionic acid
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제품정보 (DICE 배송 시 비용 별도)
Linear Formula:
HSCH2CH(NH2)CO2H
CAS 번호:
Molecular Weight:
121.16
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
200-158-2
MDL number:
Beilstein/REAXYS Number:
1721408
biological source
non-animal source
Quality Level
product line
BioReagent
assay
≥98%
form
crystalline powder
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
mp
240 °C (dec.) (lit.)
solubility
H2O: 25 mg/mL
SMILES string
N[C@@H](CS)C(O)=O
InChI
1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1
InChI key
XUJNEKJLAYXESH-REOHCLBHSA-N
General description
L-Cysteine is a proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. Cysteine is essential and limiting for the formation of glutathione, an important antioxidant, within the cell.
L-Cysteine is one of the sulfur containing proteinogenic amino acid incorporated into proteins as directed by the genetic code. The thiol-side chain participates in a variety of oxidation/reduction reactions within the cell. The side chain participates in the formation of β bonds that modulate the secondary and ternary structure of proteins. L-Cysteine is an essential precursor for inorganic sulfates, coenzyme A. Cysteine is an essential and limiting for the formation of glutathione, an important antioxidant, within the cell. Mammalian liver can synthesize L-cysteine and is a semi-essential amino acid. L-cysteine prevents oxidation of nerve cells, aids in maintaining the stability and rigidity of connective tissues. L-cysteine speeds up the healing process of the body and reduces inflammatory reactions. L-cysteine protects testis partially against acrylamide induced toxicity. L-cysteine can prevent DNA damage during cryopreservation and preserves semen quality.
Application
L-Cysteine has been used:
- as a media supplement in Trypticase-Yeast Extract-Iron-Serum (TYI-S-33) media for the culture of Giardia lamblia, to make enzyme solution in Dulbecco′s modified Eagles medium (DMEM) to establish hippocampus culture
- to test its protective effect on acrylamide induced toxicity in testis
- in the preparation of tris acetic acid extender solution for cryopreservation of semen
- as an additive to make papain digestion solution
Biochem/physiol Actions
NMDA glutamatergic receptor agonist.
Other Notes
L-Cysteine is used to supplement cell culture media. This product is a non-animal source amino acid useful for serum-free media formulations intended for biomanufacturing applications.
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저장 등급
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
문서
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.
Amino Acid Codon Wheel for fast RNA translation. Find which amino acid is translated from your RNA sequence quickly and easily.
Fibroblast growth factor 23 signaling in hippocampal cells: impact on neuronal morphology and synaptic density
Hensel N, et al.
Journal of Neurochemistry, 137(5), 756-769 (2016)
An image-based assay for high throughput screening of Giardia lamblia
Gut J, et al.
Journal of Microbiological Methods, 84(3), 398-405 (2011)
Preparation of rat brain aggregate cultures for neuron and glia development studies
Koito H and Li J
Journal of Visualized Experiments, (31), 1304-1304 (2009)