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Merck

F3917

Forskolin

For use in molecular biology applications

동의어(들):

7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one, Coleonol, Colforsin

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C22H34O7
CAS 번호:
Molecular Weight:
410.50
UNSPSC Code:
12352200
NACRES:
NA.52
PubChem Substance ID:
EC Number:
266-410-9
Beilstein/REAXYS Number:
1692716
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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biological source

Coleus forskohlii

Quality Level

description

for activation of T cells

product line

BioReagent

assay

≥98% (HPLC)

form

powder

mol wt

410.50  g/mol

color

white to off-white

solubility

ethanol: soluble

suitability

suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells

storage temp.

room temp

SMILES string

CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C

InChI

1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

InChI key

OHCQJHSOBUTRHG-KGGHGJDLSA-N

General description

Forskolin is a cell permeable diterpenoid isolated from Coleus forskohlii.

Biochem/physiol Actions

Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Dermal

저장 등급

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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시험 성적서(COA)

Lot/Batch Number

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프로토콜

Learn how to cultivate similar-sized iPSC-derived colon organoids using Millicell® Microwell plates and perform a forskolin-induced swelling assay.

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