H7125
Histamine
≥97% (TLC), powder, H₁ and H₂ histamine receptor agonist
동의어(들):
2-(4-Imidazolyl)ethylamine
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C5H9N3
CAS 번호:
Molecular Weight:
111.15
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352116
EC Number:
200-100-6
MDL number:
Beilstein/REAXYS Number:
2012
Assay:
≥97.0%
제품 이름
Histamine, ≥97.0%
Quality Segment
assay
≥97.0%
bp
167 °C/0.8 mmHg (lit.)
mp
83-84 °C (lit.)
storage temp.
−20°C
SMILES string
NCCc1c[nH]cn1
InChI
1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
InChI key
NTYJJOPFIAHURM-UHFFFAOYSA-N
Gene Information
human ... CA1(759), CA2(760), HRH1(3269), HRH2(3274), HRH3(11255), HRH4(59340)
rat ... Hrh1(24448), Hrh3(85268)
General description
Histamine is a neurotransmitter produced by neurons of the posterior hypothalamus. In the brain, histamine is predominantly present in the gray matter.
Application
Histamine has been used:
- to stimulate regulated cellular secretion
- in reaction mixture to activate blood for assaying thrombin (factor iia) activity by fluorimetry
- to fill the luminal side of the chamber to investigate its effects on the TJ-related barrier and the expression of TJ (tight junction) markers in the vocal fold epithelium
Biochem/physiol Actions
Histamine participates in innate and acquired immune response, mediating allergy and inflammation. It helps in intestinal muscle contraction. During anaphylactic shock histamine causes bronchial constriction. Histamine is also involved in gastric acid secretion, epithelial and endothelial barrier control.
Endogenous H1 and H2 histamine receptor agonist; H1 activation mobilizes Ca2+; H2 activation stimulates adenylate cyclase activity in neurons; activates nitric oxide synthetase; potent vasodilator.
Endogenous H1 and H2 histamine receptor agonist; activates nitric oxide synthetase; potent vasodilator.
Still not finding the right product?
Explore all of our products under Histamine
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves