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Merck

P3032

Penicillin G sodium salt

powder, suitable for cell culture, BioReagent

동의어(들):

Benzylpenicillin sodium salt

조직 및 계약 가격을 보려면 로그인를 클릭합니다.

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C16H17N2NaO4S
CAS 번호:
Molecular Weight:
356.37
NACRES:
NA.76
PubChem Substance ID:
eCl@ss:
34010400
UNSPSC Code:
12352207
EC Number:
200-710-2
MDL number:
Beilstein/REAXYS Number:
3834217
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제품 이름

Penicillin G sodium salt, powder, BioReagent, suitable for cell culture

InChI key

FCPVYOBCFFNJFS-LQDWTQKMSA-M

InChI

1S/C16H18N2O4S.Na/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9;/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22);/q;+1/p-1/t11-,12+,14-;/m1./s1

SMILES string

[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)Cc3ccccc3)C([O-])=O

product line

BioReagent

form

powder

potency

≥1477 units per mg

technique(s)

cell culture | mammalian: suitable

solubility

H2O: 100 mg/mL

antibiotic activity spectrum

Gram-positive bacteria

mode of action

cell wall synthesis | interferes

storage temp.

2-8°C

Quality Level

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General description

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for extended periods. Solutions are stable at 37°C for 3 days.
Chemical structure: β-lactam

Application

Penicillin G is a narrow spectrum natural antibiotic. It is effective against Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. It has been used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility and in cell culture both alone and combined with streptomycin and other antibiotics.

Biochem/physiol Actions

Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking.

Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria.

Other Notes

1mu,10mu,25mu,100mu
Keep container tightly closed in a dry and well-ventilated place.Product contains Penicillin Keep in a dry place.

Disclaimer

Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Sens. 1

저장 등급

11 - Combustible Solids

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Paul P Drury et al.
Neuropharmacology, 83, 62-70 (2014-04-15)
Basal ganglia injury after hypoxia-ischemia remains common in preterm infants, and is closely associated with later cerebral palsy. In the present study we tested the hypothesis that a highly selective neuronal nitric oxide synthase (nNOS) inhibitor, JI-10, would improve survival
Ana Amaral et al.
Frontiers in veterinary science, 7, 582211-582211 (2020-11-17)
Although proteases found in neutrophil extracellular traps (NETs) have antimicrobial properties, they also stimulate collagen type 1 (COL1) production by the mare endometrium, contributing for the development of endometrosis. Cathepsin G (CAT), a protease present in NETs, is inhibited by
Fleury Augustin Nsole Biteghe et al.
Journal of photochemistry and photobiology. B, Biology, 211, 111982-111982 (2020-09-01)
Aberrant anti-cancer drug efflux mediated by membrane protein ABC transporters (ABCB5 and ABCG2) is thought to characterize melanoma heterogeneous chemoresistant populations, presumed to have unlimited proliferative and self-renewal abilities. Therefore, this study primarily aimed to investigate whether continuous exposure of
Zhichao Guan et al.
Analytical chemistry, 86(5), 2789-2797 (2014-02-11)
Microfabricated devices are suitable for single-cell analysis due to their high throughput, compatible dimensions and controllable microenvironment. However, existing devices for single-cell culture and analysis encounter some limitations, such as nutrient depletion, random cell migration and complicated fluid shear influence.
Maria Eugenia Sabatino et al.
Frontiers in cell and developmental biology, 7, 297-297 (2019-12-12)
Krüppel-like factor 6 (KLF6) is a transcription factor involved in the regulation of several cellular processes. Regarding its role in tumorigenesis, KLF6 is considered a tumor suppressor. Numerous reports demonstrate its frequent genomic loss or down-regulation, implying a functional inactivation

문서

β-lactam antibacterials inhibit transpeptidase enzymes, preventing peptidoglycan assembly in both Gram-positive and Gram-negative bacteria.

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