R9644
Ribavirin
≥98% (TLC), IMP dehydrogenase inhibitor, powder
동의어(들):
1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
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제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C8H12N4O5
CAS 번호:
Molecular Weight:
244.20
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.77
MDL number:
제품 이름
Ribavirin, antiviral
Quality Segment
assay
≥98% (TLC)
form
powder
solubility
water: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
antibiotic activity spectrum
viruses
mode of action
DNA synthesis | interferes
storage temp.
2-8°C
SMILES string
NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
InChI
1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1
InChI key
IWUCXVSUMQZMFG-AFCXAGJDSA-N
Gene Information
human ... IMPDH1(3614), IMPDH2(3615)
General description
Analog of the imidazole nucleotide intermediates in purine nucleotide biosynthesis.
Chemical structure: nucleoside
Biochem/physiol Actions
Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase, but many other mechanisms of action are also supported with experimental evidence.
Antiviral agent used against a wide variety of human viral infections, in particular, chronic hepatitis C, HIV, and adenovirus. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase.
Antiviral agent. Its metabolite, ribavirin 5′-phosphate, is an inhibitor of inosine monophosphate (IMP) dehydrogenase. Used to inhibit purine (GTP pools) biosynthesis at the level of inosine monophosphate (IMP) dehydrogenase and as a precursor to the di- and tri-phosphates which inhibit viral RNA-dependent RNA polymerases.
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signalword
Danger
hcodes
Hazard Classifications
Muta. 2 - Repr. 1B
저장 등급
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges