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171254

Ampicillin, Sodium Salt

Name: Ampicillin, Sodium Salt
Brand: MM

Ampicillin salt is an antibiotic that inhibits bacterial cell-wall synthesis. Active against Gram-negative bacteria. Inactivated by lactamases. Suitable for use in research that uses ampicillin-resistant plasmids.

Synonym(s):

Ampicillin, Sodium Salt, 6-[D(–)-α-Aminophenylacetamido]penicillanic Acid, Na, Alpha-Aminobenzyl Penicillin, Ampicillin

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₈N₃O₄S · Na

CAS Number:

69-52-3

Molecular Weight:

371.39

UNSPSC Code:

41116107

MDL number:

MFCD00064313

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Properties

Quality Segment

100

assay

≥90% (anhydrous)

form

solid

manufacturer/tradename

Calbiochem^®

storage condition

OK to freeze, desiccated (hygroscopic)

color

white

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

SMILES string

[Na+].S1[C@H]2N([C@H](C1(C)C)C(=O)[O-])C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3

InChI

1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1

InChI key

KLOHDWPABZXLGI-YWUHCJSESA-M

Description

General description

Kills growing cells by interfering with the terminal reaction in bacterial wall synthesis. Active against Gram-negative bacteria. Inactivated by lactamases. Suitable for use in research that uses ampicillin-resistant plasmids.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C. Product is heat-resistant and stable between pH 2 and 11.

Other Notes

Nakajima, M., et al. 1994. Neurosci. Lett.176, 161.
Wu, M.H., and Yung, B.Y. 1994. Eur. J. Pharmacol.270, 203.
Betzel, C., et al. 1993. Biochim. Biophys. Acta1161, 47.
Yung, B.Y., et al. 1992. Int. J. Cancer52, 317.
Martin, S.J., et al. 1990. J. Immunol.145, 1859.
Yung, B.Y., et al. 1990. Cancer Res.50, 5987.
White, R.J., and Phillips, D.R. 1985. Biochemistry27, 9122.
Madharavao, M., et al. 1978. J. Med. Chem. 21, 958.
Sengupta, S.K., et al. 1975. J. Med. Chem. 18, 1175.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Irritant (B)

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pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1A - Skin Sens. 1A

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c