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Merck

B1385

Butoxamine hydrochloride

analytical standard, for drug analysis, mixture of diastereomers

Synonym(s):

α-(1-[t-Butylamino]ethyl)-2,5-dimethoxybenzyl alcohol

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About This Item

Empirical Formula (Hill Notation):
C15H25NO3 · HCl
CAS Number:
5696-15-1
Molecular Weight:
303.82
NACRES:
NA.24
PubChem Substance ID:
329773182
UNSPSC Code:
41116107
EC Number:
227-169-5
MDL number:
MFCD00135781

Key Documents

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InChI key

URPAECSKKQLCII-UHFFFAOYSA-N

InChI

1S/C15H25NO3.ClH/c1-10(16-15(2,3)4)14(17)12-9-11(18-5)7-8-13(12)19-6;/h7-10,14,16-17H,1-6H3;1H

SMILES string

Cl.COc1ccc(OC)c(c1)C(O)C(C)NC(C)(C)C

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

200

Related Categories

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Butoxamine hydrochloride is a β-andrenoceptor antagonist, which shows β2-selectivity.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCK2541
SLCH6710
SLCC4660
SLBW8626
SLBT4317

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Concise Dictionary of Pharmacological Agents: Properties and Synonyms null
Farideh Beigi et al.
Analytical chemistry, 76(24), 7187-7193 (2004-12-15)
Membranes from a HEK-293 cell line expressing the beta(2)-adrenergic receptor (beta(2)-AR) have been immobilized on an artificial membrane liquid chromatographic stationary phase. The resulting phase was packed into a glass column (1.8 x 0.5 (i.d.) cm) and used in on-line
Haruto Kato et al.
Anesthesia and analgesia, 108(1), 288-295 (2008-12-20)
Proinflammatory cytokines increase in cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH). Recent evidence suggested that beta-adrenoceptor antagonist could reduce proinflammatory cytokines. We conducted the present study to examine whether beta-adrenoceptor antagonists would reduce proinflammatory cytokine concentrations after SAH in rats.
Dong Zhang et al.
Pancreas, 38(1), 94-100 (2008-12-25)
Propranolol inhibited pancreatic cancer cell proliferation by blocking signaling through the beta-adrenoceptor. We hypothesized that propranolol may suppress pancreatic cancer cell growth through induction of apoptosis. The beta-adrenoceptor antagonist propranolol, beta1-adrenoceptor antagonist metoprolol, and beta2-adrenoceptor antagonist butoxamine were used to
Nan Yang et al.
Respiratory research, 22(1), 65-65 (2021-02-25)
Airway inflammation is a key feature of chronic obstructive pulmonary disease (COPD) and inhaled corticosteroids (ICS) remain the main treatment for airway inflammation. Studies have noted the increased efficacy of ICS and long-acting beta 2 agonist (LABA) combination therapy in
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