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Merck

ED

Ethylenediaminetetraacetic acid

purified grade, ≥98.5%, powder

Synonym(s):

(Ethylenedinitrilo)tetraacetic acid, EDTA, Edathamil, Ethylenedinitrilotetraacetic acid

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About This Item

Linear Formula:
(HO2CCH2)2NCH2CH2N(CH2CO2H)2
CAS Number:
60-00-4
Molecular Weight:
292.24
NACRES:
NA.28
PubChem Substance ID:
24894707
eCl@ss:
39030907
UNSPSC Code:
12352116
EC Number:
200-449-4
MDL number:
MFCD00003541
Beilstein/REAXYS Number:
1716295

Key Documents

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InChI key

KCXVZYZYPLLWCC-UHFFFAOYSA-N

InChI

1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)

SMILES string

OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O

grade

purified grade

assay

≥98.5%

form

powder

reaction suitability

reagent type: chelator

pH

2.5 (23 °C, 10 g/L)

mp

250 °C (dec.) (lit.)

Quality Level

200

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General description

Ethylenediaminetetraacetic acid (EDTA) is an affordable chelating agent. It is an aminopolycarboxylic acid and a hexadentate ligand and forms octahedral complex with cations. Ethylenediaminetetraacetic acid (EDTA) is not recommended for phytoremediation as it can leach into natural water resources. It is used in cosmetics and pharmaceutical industry. It triggers platelet aggregation in pseudothrombocytopenia. In chelation therapy, it elicits protection from oxidative damage during blood and lipid peroxidation and may be useful to treat cardiovascular and carbon tetrachloride induced liver fibrosis.

Application

Ethylenediaminetetraacetic acid may be used:
  • as a component of staining buffer
  • as buffer component for incubating epithelial cell adhesion molecule (EpCAM+) cells with fluorescein isothiocyanate (FITC)-conjugated antibody for cell sorting studies
  • for treating epithelial cells for isolation of mucosal myofibroblasts

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

target_organs

Respiratory Tract

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - STOT RE 2 Inhalation

wgk

WGK 3

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG3397
BCCF8249
BCCF0095
BCCD7593
BCCC1984

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Functional modulation of Crohn?s disease myofibroblasts by anti-tumor necrosis factor antibodies
Di Sabatino A, et al.
Gastroenterology, 133(1), 137-149 (2007)
Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis
Bartholome B, et al.
Faseb Journal, 18(1), 70-80 (2004)
The phenotypes of pluripotent human hepatic progenitors
Schmelzer E, et al.
Stem Cells, 24(8), 1852-1858 (2006)
Induced Plant Accumulation of Lithium
Kavanagh L, et al.
Geostandards Newsletter, 8(2), 56-56 (2018)
Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis
Gonzalez-Cuevas J, et al.
Redox Report, 16(2), 62-70 (2011)
View All Related Papers

Global Trade Item Number

SKUGTIN
MAB143504053252610950
EDSPAK00104053252468704
EDSPAK0A104054839323430
S8005H04053252908934

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