Key Documents

View All Documentation

PHR1051

Propylene glycol

Name: Propylene glycol
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(s):

1,2-Propanediol, Propylene glycol

Select a Size

Change View

About This Item

Linear Formula:

CH₃CH(OH)CH₂OH

CAS Number:

57-55-6

Molecular Weight:

76.09

NACRES:

NA.24

E Number:

E1520

PubChem Substance ID:

329823081

UNSPSC Code:

41116107

EC Number:

200-338-0

MDL number:

MFCD00064272

Beilstein/REAXYS Number:

1340498

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1576708

vapor density

2.62 (vs air)

vapor pressure

0.08 mmHg ( 20 °C)

API family

propylene glycol

CofA

current certificate can be downloaded

autoignition temp.

779 °F

expl. lim.

12.5 %

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.432 (lit.)

bp

187 °C (lit.)

mp

−60 °C (lit.)

density

1.036 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

CC(O)CO

InChI

1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3

InChI key

DNIAPMSPPWPWGF-UHFFFAOYSA-N

Description

General description

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propylene glycol is commonly utilized as a penetration enhancer in topical dermatological formulations, either alone or in combined form with other penetration enhancing agents, like fatty acids.

Application

Propylene glycol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

To see an example of a Certificate of Analysis for this material enter LRAB9658 in the slot below. This is an example certificate only and may not be the lot that you receive.

Still not finding the right product?

Explore all of our products under Propylene glycol

Storage Class

10 - Combustible liquids

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library