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About This Item
Linear Formula:
Na2HPO4
CAS Number:
Molecular Weight:
141.96
PubChem Substance ID:
eCl@ss:
38070211
UNSPSC Code:
12352302
NACRES:
NA.21
EC Number:
231-448-7
MDL number:
Quality Level
grade
ACS reagent
agency
suitable for SM 5210
assay
≥99.0%
form
powder
impurities
≤0.002% Chloride (Cl), ≤0.01% Insoluble matter
loss
≤0.2% loss on drying, 105°C
pH
8.7-9.3 (25 °C, 5% in solution)
pKa (25 °C)
(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)
solubility
water: 5% at 25 °C, clear
anion traces
sulfate (SO42-): ≤0.005%
cation traces
Fe: ≤0.002%, heavy metals: ≤0.001% (by ICP-OES)
SMILES string
[Na+].[Na+].[H]OP([O-])([O-])=O
InChI
1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
InChI key
BNIILDVGGAEEIG-UHFFFAOYSA-L
General description
Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.
Application
Sodium phosphate dibasic has been used in:
- the preparation of phosphate buffer saline solution for perfusion procedure
- western blot
- indirect enzyme linked immunosorbent assay
Other Notes
Legal Information
Redi-Dri is a trademark of Sigma-Aldrich Co. LLC
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Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Glomerular calcification induced by bolus injection with dibasic sodium phosphate solution in Sprague-Dawley rats
Tsuchiya N, et al.
Toxicologic Pathology, 408-412 (2004)
Peri H Tate et al.
Methods (San Diego, Calif.), 53(4), 331-338 (2011-02-04)
The EUCOMM and KOMP programs have generated targeted conditional alleles in mouse embryonic stem cells for nearly 10,000 genes. The availability of these stem cell resources will greatly accelerate the functional analysis of genes in mice and in cultured cells.
Karsten Krug et al.
Cell, 183(5), 1436-1456 (2020-11-20)
The integration of mass spectrometry-based proteomics with next-generation DNA and RNA sequencing profiles tumors more comprehensively. Here this "proteogenomics" approach was applied to 122 treatment-naive primary breast cancers accrued to preserve post-translational modifications, including protein phosphorylation and acetylation. Proteogenomics challenged