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Merck

287571

Bis(2,2,2-trifluoroethyl) ether

98%

Synonym(s):

2,2,2-Trifluoroethyl ether, Flurothyl

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About This Item

Linear Formula:
(CF3CH2)2O
CAS Number:
333-36-8
Molecular Weight:
182.06
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24857279
MDL number:
MFCD00010604
Beilstein/REAXYS Number:
1811927

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Product Name

Bis(2,2,2-trifluoroethyl) ether, 98%

InChI

1S/C4H4F6O/c5-3(6,7)1-11-2-4(8,9)10/h1-2H2

SMILES string

FC(F)(F)COCC(F)(F)F

InChI key

KGPPDNUWZNWPSI-UHFFFAOYSA-N

assay

98%

form

liquid

refractive index

n20/D 1.300 (lit.)

bp

62-63 °C (lit.)

density

1.404 g/mL at 25 °C (lit.)

functional group

ether
fluoro

Quality Level

100

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Application

Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

33.8 °F - closed cup

flash_point_c

1 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ9734
MKCQ1437
MKCP0541
MKCN3689
MKCL7103

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Omar I Khan et al.
Neurobiology of disease, 39(3), 362-371 (2010-05-11)
Frequent interictal spikes are a common finding in the electroencephalograms of children with epileptic encephalopathies. While it is well recognized that interictal spikes are a biological marker of seizures and can lead to transitory cognitive impairment, whether interictal spikes can
Havisha B Karnam et al.
Epilepsy research, 85(2-3), 221-230 (2009-04-28)
Clinical studies have suggested that seizures in newborns are more damaging than seizures occurring in older children. However, these studies are difficult to interpret for a variety of factors including differing etiologies of seizures across ages. Animal studies can provide
Megan Leigh Lewis et al.
Epilepsia, 59(7), 1316-1326 (2018-06-03)
In different cohorts, 5%-30% of individuals with autism spectrum disorder (ASD) also have epilepsy. The high co-occurrence of these disorders suggests that a common mechanistic link may exist. The underlying pathophysiology of this comorbidity remains unknown. To investigate the mechanism(s)
Stacey B B Dutton et al.
Epilepsia, 52(11), 2050-2056 (2011-08-02)
We evaluated the ability of the ketogenic diet (KD) to improve thresholds to flurothyl-induced seizures in two mouse lines with Scn1a mutations: one that models Dravet syndrome (DS) and another that models genetic (generalized) epilepsy with febrile seizures plus (GEFS+).
Yogendrasinh H Raol et al.
Annals of neurology, 65(3), 326-336 (2009-04-01)
Neonatal seizures occur frequently, are often refractory to anticonvulsants, and are associated with considerable morbidity and mortality. Genetic and electrophysiological evidence indicates that KCNQ voltage-gated potassium channels are critical regulators of neonatal brain excitability. This study tests the hypothesis that
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