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About This Item
Linear Formula:
15NH4Cl
CAS Number:
Molecular Weight:
54.48
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12142200
MDL number:
Product Name
Ammonium-15N chloride, ≥98 atom % 15N, ≥99% (CP)
InChI
1S/ClH.H3N/h1H;1H3/i;1+1
SMILES string
[15NH4+].[Cl-]
InChI key
NLXLAEXVIDQMFP-IEOVAKBOSA-N
isotopic purity
≥98 atom % 15N
assay
≥99% (CP)
form
powder, crystals or chunks
technique(s)
bio NMR: suitable
protein expression: suitable
mp
340 °C (subl.) (lit.)
mass shift
M+1
storage temp.
room temp
Quality Level
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Application
Ammonium-15N chloride has been used:
- as a medium supplement for the incorporation of 15N in sporulation protein, CsfB, for NMR spectroscopy
- in assaying nitrogen loss in marine sediment
- for the incorporation of 15N in apolipoprotein A-I for mass spectrum analysis
Biochem/physiol Actions
Ammonium chloride is a component of the nitrogen cycle. Excess of ammonium chloride depletes ATP in astrocytes. Ammonium chloride inhibits the acidification in endosome-lysosome system. It is a hemolysing agent used in the lysis of erythrocytes. Ammonium chloride administration promotes creatinine and urea clearance in rat.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
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Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
13 - Non Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds?a critical review
Buffet-Bataillon S, et al.
International Journal of Antimicrobial Agents, 39(5), 381-389 (2012)
Anaerobic ammonium oxidation linked to sulfate and ferric iron reduction fuels nitrogen loss in marine sediments
Rios-Del T, et al.
Biodegradation, 29(5), 429-442 (2018)
Characterization of homodimer interfaces with cross-linking mass spectrometry and isotopically labeled proteins
Lima DB, et al.
Nature Protocols, 13(3), 431-431 (2018)
Journal of the Chemical Society. Chemical Communications, 62-62 (1982)
Thomas Wiegand et al.
Journal of biomolecular NMR, 65(2), 79-86 (2016-06-01)
The use of protein building blocks for the structure determination of multidomain proteins and protein-protein complexes, also known as the "divide and conquer" approach, is an important strategy for obtaining protein structures. Atomic-resolution X-ray or NMR data of the individual
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