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Merck

54965

(±)-Sodium 3-hydroxybutyrate

≥99.0% (NT)

Synonym(s):

(±)-3-Hydroxybutyric acid sodium salt

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About This Item

Linear Formula:
CH3CH(OH)CH2COONa
CAS Number:
Molecular Weight:
126.09
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-774-5
Beilstein/REAXYS Number:
4824866
MDL number:
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Product Name

(±)-Sodium 3-hydroxybutyrate, ≥99.0% (NT)

InChI key

NBPUSGBJDWCHKC-UHFFFAOYSA-M

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

SMILES string

[Na+].CC(O)CC([O-])=O

assay

≥99.0% (NT)

mp

167-170 °C

functional group

hydroxyl

Quality Level

Related Categories

Application

(±)-Sodium 3-hydroxybutyrate has been used in a study to understand the effect of butyrate on fibroblast growth factor 21 (FGF21), which is involved in fatty acid ß-oxidation in liver. It may be used in the preparation of poly(3-hydroxybutyrate).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Nikolaj Rittig et al.
Shock (Augusta, Ga.), 44(1), 32-35 (2015-04-22)
Endotoxin administrations are used in experimental models of inflammatory disease. Short-term endotoxin tolerance in response to repeated endotoxin exposure is well known, but the duration of endotoxin tolerance in humans remains unknown. The main purpose of this study was to
Stephanie Lilja et al.
Oxidative medicine and cellular longevity, 2020, 4793125-4793125 (2020-11-06)
We investigated different bioactive compounds including epigallocatechin gallate (EGCG), anthocyanidin, resveratrol, phloretin, spermidine, butyrate, and β-hydroxybutyrate with regard to their effect on SIRT3 via NRF2 and modulation of the proinflammatory senescence-associated secretory phenotype (SASP) in senescence induced 3T3-L1 preadipocytes. For

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