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About This Item
Linear Formula:
(C6H10O2)n
NACRES:
NA.21
UNSPSC Code:
12162002
Product Name
Polycaprolactone, average Mn 45,000
form
pellets
melt index
1.8 g/10 min (80 °C, 44 psi)
mol wt
Mn 40,000-50,000
Mw 48,000-90,000
average Mn 45,000
mp
56-64 °C
60 °C (lit.)
Quality Level
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Application
PCL can form a nanocomposite with graphene for the fabrication of biodegradable systems for bone tissue engineering.
Features and Benefits
Biodegradable polymer
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.
Non-toxic, biodegradable in soil, broad miscibility, mechanical compatibility with many polymers and good adhesion to a broad spectrum of substrates.
General description
Polycaprolactone (PCL) is a semi-crystalline linear resorbable aliphatic polyester that is composed of repeating units of hexanoate. It has good mechanical properties, miscibility, and biodegradability. PCL is a soft and hard-tissue compatible material that can be used in sutures and drug delivery systems.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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A novel degradable polycaprolactone networks for tissue engineering
Kweon H, et al.
Biomaterials, 24(5), 801-808 (2003)
Bone tissue engineering using polycaprolactone scaffolds fabricated via selective laser sintering
Williams JM, et al.
Biomaterials, 26(23), 4817-4827 (2005)
Synthesis of polycaprolactone: a review
Labet M and Thielemans W
Chemical Society Reviews, 38(12), 3484-3504 (2009)
Properties of thermoplastic blends: starch-polycaprolactone
Averous L, et al.
Polymer, 41(11), 4157-4167 (2000)
Wendi Zhang et al.
Biomaterials, 34(27), 6495-6503 (2013-06-04)
Coating the polycation/DNA binary complexes with PEGylated polyanions can improve long-circulation and biocompatibility in vivo. However, it has been certificated PEG dilemma can reduces gene transfection efficiency because of inhibition in cellular uptake and endosomal escape. Herein, two PEGylated anionic
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