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Merck

D208000

1,6-Diphenyl-1,3,5-hexatriene

98%

Synonym(s):

DPH, Dicinnamyl

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About This Item

Linear Formula:
C6H5(CH=CH)3C6H5
CAS Number:
Molecular Weight:
232.32
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
217-011-3
Beilstein/REAXYS Number:
1907440
MDL number:
Assay:
98%
Form:
crystals
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InChI

1S/C18H16/c1(5-11-17-13-7-3-8-14-17)2-6-12-18-15-9-4-10-16-18/h1-16H/b2-1+,11-5+,12-6+

InChI key

BOBLSBAZCVBABY-WPWUJOAOSA-N

SMILES string

C(=C/C=C/c1ccccc1)\C=C\c2ccccc2

assay

98%

form

crystals

mp

199-203 °C (lit.)

fluorescence

λex 350 nm; λem 452 nm in methanol

Quality Level

General description

DPH is a lipophilic molecule used to study membrane fluidity and polarization by measuring its fluorescence properties.

Application

Used an alternative to Nile red for fluorescent detection of lipid droplets

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Mineko Terao et al.
Journal of experimental & clinical cancer research : CR, 38(1), 436-436 (2019-10-31)
All-trans-retinoic-acid (ATRA) is a promising agent in the prevention/treatment of breast-cancer. There is growing evidence that reprogramming of cellular lipid metabolism contributes to malignant transformation and progression. Lipid metabolism is implicated in cell differentiation and metastatic colonization and it is
Mengya Li et al.
The journal of physical chemistry. B, 123(31), 6784-6791 (2019-07-16)
How to reduce the cytotoxicity of antitumor peptides to normal cells remains an ongoing challenge. Here, we designed a pH/redox-responsive supramolecular structure (Pep-V⊂P-PEG) composed of a peptide modified with viologen (Pep-V) and polyethylene glycol bearing pillar[5]arene (P-PEG) as a "helmet".
Natalie Spang et al.
Autophagy, 10(12), 2297-2309 (2014-12-17)
Macroautophagy is a degradative pathway that sequesters and transports cytosolic cargo in autophagosomes to lysosomes, and its deterioration affects intracellular proteostasis. Membrane dynamics accompanying autophagy are mostly elusive and depend on trafficking processes. RAB GTPase activating proteins (RABGAPs) are important
Selma Y Dejgaard et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 66(6), 447-465 (2018-01-24)
Determination of lipid droplet (LD) volume has depended on direct measurement of the diameter of individual LDs, which is not possible when LDs are small or closely apposed. To overcome this problem, we describe a new method in which a
Md Jafurulla et al.
Biochimica et biophysica acta, 1838(1 Pt B), 158-163 (2013-09-07)
The serotonin1A receptor is an important member of the G protein-coupled receptor (GPCR) family. It is involved in the generation and modulation of a variety of cognitive and behavioral functions and serves as a drug target. Previous work from our

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