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About This Item
Empirical Formula (Hill Notation):
C37H66N5O11P
CAS Number:
Molecular Weight:
787.92
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352211
Product Name
16:0-12:0 NBD PA, Avanti Research™ - A Croda Brand 810174P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810174P-1mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 810174P
shipped in
dry ice
storage temp.
−20°C
General description
Phosphatidic acid (PA) is a simple anionic cellular glycerophospholipid possessing a phosphomonoester polar head group and two long hydrophobic acyl chains. 7-nitro-2-1,3-benzoxadiazol-4-yl (NBD) PA is a fluorophore labeled phospholipid having 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the sn-2 fatty acid of PA.
Application
16:0-12:0 NBD PA or 1-palmitoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt) is suitable:
- to incubate cells for the imaging of lyso phosphatidylcholine (PC) in P. falciparum live cells
- as a component of separation buffer for the separation of phosphoinositides and sphingolipids in the microchip devices
- in cytidine diphosphate diacylglycerol (CDP-DAG) synthase activity assay
Biochem/physiol Actions
Phosphatidic acid (PA) influences membrane fusion and membrane fission events and membrane curvature. It acts as a signaling molecule for various cellular processes including membrane trafficking and sperm hyper-activation.
Packaging
5 mL Amber Glass Screw Cap Vial (810174P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Storage Class
11 - Combustible Solids
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