Skip to Content
Merck

810195C

Avanti

18:1-12:0 NBD PS

Avanti Research™ - A Croda Brand

Synonym(s):

1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt)

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C42H73N6O13P
CAS Number:
474943-00-5
Molecular Weight:
901.04
MDL number:
MFCD09751057
NACRES:
NA.25
UNSPSC Code:
12352211

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

18:1-12:0 NBD PS, Avanti Research™ - A Croda Brand 810195C

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 1 mL (810195C-1mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 810195C

concentration

1 mg/mL (810195C-1mg)

shipped in

dry ice

storage temp.

−20°C

Application

18:1-12:0 NBD PS or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphoserine (ammonium salt) has been used in donor liposomes to determine the phospholipid transfer activity of the synaptic vesicle membrane protein, VAT-1 and phosphatidic acid (PA) transfer by Ups1−Mdm35 system in mitochondria. 18:1-12:0 NBD PS is also suitable for the determination of in vitro phosphatidylserine decarboxylase (Psd1) activity.

General description

Phosphatidylserine (PS) is a minor membrane phospholipid. This anionic phospholipid contains a polar head group and two long hydrophobic acyl chains. 1 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) PS is a fluorescent probe containing NBD at the headgroup of PS.

Packaging

5 mL Amber Glass Screw Cap Vial (810195C-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

target_organs

Central nervous system, Liver,Kidney

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

67-66-3

CAS No.

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER
Jonathan R, et al.
Developmental Cell null
The distribution and function of phosphatidylserine in cellular membranes
Leventis PA and Grinstein S
Annual Review of Biophysics null
Structural and mechanistic insights into phospholipid transfer by Ups1?Mdm35 in mitochondria
Yasunori W, et al.
Nature Communications null
Jonathan R Friedman et al.
Developmental cell, 44(2), 261-270 (2018-01-02)
Spatial organization of phospholipid synthesis in eukaryotes is critical for cellular homeostasis. The synthesis of phosphatidylcholine (PC), the most abundant cellular phospholipid, occurs redundantly via the ER-localized Kennedy pathway and a pathway that traverses the ER and mitochondria via membrane
Muhasin Koyiloth et al.
European biophysics journal : EBJ, 49(2), 163-173 (2020-02-06)
In this study, the SCRM-1 gene from Caenorhabditis elegans was cloned and overexpressed in E. coli to study the biochemical properties of scramblase. This is the first report showing that this scramblase from C. elegans possesses a Ca2+-dependent and head
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service