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Merck

841138C

Avanti

Egg PG

Avanti Research™ - A Croda Brand

Synonym(s):

L-α-phosphatidylglycerol (Egg, Chicken) (sodium salt)

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About This Item

CAS Number:
383907-64-0
MDL number:
MFCD00674290
UNSPSC Code:
12352211
NACRES:
NA.25

Key Documents

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InChI key

FJXDNGDRHUDFST-XQYKCTAGSA-M

SMILES string

[H][C@@](COP([O-])(OCC(O)CO)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]

assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (841138C-25mg), pkg of 2 × 4 mL (841138C-200mg), pkg of 5 × 4 mL (841138C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (841138C-25mg), 25 mg/mL (841138C-200mg), 25 mg/mL (841138C-500mg)

lipid type

phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

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General description

Phosphatidylglycerol (PG) is one of the major phospholipids in food and biological tissues. PG is the anionic phospholipid in the membranes of Staphylococcus sp. and Escherichia coli. PG is present in low amounts in mammalian membranes. Structurally, PG has two acyl chains esterified to a glycerol, bonded to a headgroup structure that has phosphate and carries negative charge. PG is synthesized from cytidine phosphate-diacylglycerol (CDP-DAG).

Application

Egg PG has been used:
  • as a phospholipid to test the binding ability of SEIPIN, an integral membrane protein of endoplasmic recticulum
  • as a standard for photodynamic treatment
  • as a standard for the identification of phospholipids by thin layer chromatography and electrospray ionization-mass spectra (ESI-MS)

Biochem/physiol Actions

Phosphatidylglycerol (PG) is present in amniotic fluid and indicates fetal lung maturity. It functions as a precursor for cardiolipin in animals. In plants, PG is present in thylakoid membranes and plays a central role in photosynthesis.

Packaging

5 mL Clear Glass Sealed Ampule (841138C-200mg)
5 mL Clear Glass Sealed Ampule (841138C-25mg)
5 mL Clear Glass Sealed Ampule (841138C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

target_organs

Liver,Kidney, Respiratory system

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

67-66-3

CAS No.

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Photodynamic oxidation of Escherichia coli membrane phospholipids: new insights based on lipidomics
Alves E, et al.
Rapid Communications in Mass Spectrometry, 27(23), 2717-2728 (2013)
The
The Membranes of Cells, 27(23) (2016)
Eliana Alves et al.
Rapid communications in mass spectrometry : RCM, 27(23), 2717-2728 (2014-03-05)
The irreversible oxidation of biological molecules, such as lipids, can be achieved with a photosensitizing agent and subsequent exposure to light, in the presence of molecular oxygen. Although lipid peroxidation is an important toxicity mechanism in bacteria, the alterations caused
Validation of an LC-MS/MS method for the quantification of choline-related compounds and phospholipids in foods and tissues
Xiong Y, et al.
Journal of Chromatography. B, Biomedical Applications, 911, 170-179 (2012)
Michael J Volles et al.
Journal of molecular biology, 366(5), 1510-1522 (2007-01-16)
To investigate the alpha-synuclein protein and its role in Parkinson's disease, we screened a library of random point mutants both in vitro and in yeast to find variants in an unbiased way that could help us understand the sequence-phenotype relationship.
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