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Merck

846725P

Avanti

18:1 Lyso PE

Avanti Research™ - A Croda Brand

Synonym(s):

1--(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine; PE(18:1(9Z)/0:0)

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About This Item

Empirical Formula (Hill Notation):
C23H46NO7P
CAS Number:
89576-29-4
Molecular Weight:
479.59
UNSPSC Code:
51191904
NACRES:
NA.25

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InChI

1S/C23H46NO7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23(26)29-20-22(25)21-31-32(27,28)30-19-18-24/h9-10,22,25H,2-8,11-21,24H2,1H3,(H,27,28)/b10-9-/t22-/m1/s1

InChI key

PYVRVRFVLRNJLY-MZMPXXGTSA-N

SMILES string

O[C@](COP([O-])(OCC[NH3+])=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O

description

1-oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine

assay

>99% (LPE; may contain up to 10% of the 2-LPE isomer, TLC)

form

powder

packaging

pkg of 1 × 1 g (846725P-1g), pkg of 2 × 100 mg (846725P-200mg), pkg of 1 × 25 mg (846725P-25mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

lipid type

cardiolipins
phospholipids

shipped in

dry ice

storage temp.

−20°C

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General description

Lysophosphatidyletnolamine (LPE), an enigmatic lipid of bacteria is obtained from phosphatidylethanolamine during various fluctuations of the bacterial growth conditions.

Application

18:1 Lyso PE is suitable for use in the synthesis of lipid molecules. It is also suitable to use as a standard in the study of systematic optimization of hydrophilic interaction liquid chromatography-mass spectrometry (HILIC/MS) separation of acidic lipid classes.

Packaging

5 mL Clear Glass Sealed Ampule (846725P-200mg)
5 mL Clear Glass Sealed Ampule (846725P-25mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (846725P-1g)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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Opposite effects of lysophosphatidylethanolamines on conformation of OmpF-like porin from Yersinia pseudotuberculosis
Davydova AL, et al.
Protein and peptide letters, 22(12), 1060-1065 (2015)
Enzymatic formation of N-acylethanolamines from N-acylethanolamine plasmalogen through N-acylphosphatidylethanolamine-hydrolyzing phospholipase D-dependent and-independent pathways
Tsuboi K, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1811(10), 565-577 (2011)
Hydrophilic interaction liquid chromatography? mass spectrometry of (lyso) phosphatidic acids,(lyso) phosphatidylserines and other lipid classes
Cifkova E, et al.
Journal of Chromatography A, 1439, 65-73 (2016)
Svenja Bockelmann et al.
Journal of lipid research, 59(3), 515-530 (2018-01-19)
Ceramides are central intermediates of sphingolipid metabolism with dual roles as mediators of cellular stress signaling and mitochondrial apoptosis. How ceramides exert their cytotoxic effects is unclear and their poor solubility in water hampers a search for specific protein interaction

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