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857120P

Avanti

14:0 Lyso PA

Avanti Research™ - A Croda Brand

Synonym(s):

1-tetradecanoyl-sn-glycero-3-phosphate (sodium salt); PA(14:0/0:0); 14:0 LPA; 110677

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About This Item

Empirical Formula (Hill Notation):
C17H34O7PNa
CAS Number:
325465-45-0
Molecular Weight:
404.41
UNSPSC Code:
51191904
NACRES:
NA.25
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Product Name

14:0 Lyso PA, 1-myristoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt), powder

assay

>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)

form

powder

packaging

pkg of 1 × 25 mg (857120P-25mg), pkg of 1 × 500 mg (857120P-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 857120P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCC)=O.[Na+]

InChI

1S/C17H35O7P.Na/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(19)23-14-16(18)15-24-25(20,21)22;/h16,18H,2-15H2,1H3,(H2,20,21,22);/q;+1/p-1/t16-;/m1./s1

InChI key

HGENTPHNTSLRPB-PKLMIRHRSA-M

General description

Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.

Application

14:0 Lyso PA is suitable to use as internal standard to spike serum samples for the extraction of serum lipids. It is also suitable to use as standard lipids for extraction of lipids and for quality control in multiple reaction monitoring (MRM) assay.

Biochem/physiol Actions

Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca2+ mobilization, neurotransmitter release and cell proliferation.

Packaging

20 mL Clear Glass Screw Cap Vial (857120P-500mg)
5 mL Amber Glass Screw Cap Vial (857120P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

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