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About This Item
Empirical Formula (Hill Notation):
C18H37NO
CAS Number:
Molecular Weight:
283.49
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Product Name
1-deoxysphingosine, Avanti Research™ - A Croda Brand 860470P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860470P-1mg), pkg of 1 × 10 mg (860470P-10mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860470P
lipid type
bioactive lipids
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
C[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI key
ZREXGWPJFRJAJU-SWESGNQDSA-N
General description
1-deoxysphingosine (1-deoxySO) has a (4E) double bond in its structure and is synthesized by the catabolism of 1-deoxyceramide in the presence of ceramidase enzyme. It is an unsaturated deoxy-sphingoid base.
Application
1-deoxysphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing of MN9D dopaminergic neuroblastoma cell line and dorsal root ganglion neurons cultures. It may also be used as a standard for quantification of spingolipids from human plasma samples by liquid chromatography electrospray ionization tandem mass spectrometry (LC−ESI−MS/MS).
Biochem/physiol Actions
1-deoxysphingosine levels are elevated in lymphoblasts in hereditary sensory neuropathy type 1 (HSAN1) disorder.
Packaging
5 mL Amber Glass Screw Cap Vial (860470P-10mg)
5 mL Amber Glass Screw Cap Vial (860470P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
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