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860676P

Avanti

C16 Ceramide-d7 (d18:1-d7/16:0)

Name: C16 Ceramide-d7 (d18:1-d7/16:0)
Brand: AVANTI

Avanti Research^™ - A Croda Brand

Synonym(s):

N-palmitoyl-D-erythro-sphingosine (d7)

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About This Item

Empirical Formula (Hill Notation):

C₃₄H₆₀D₇NO₃

CAS Number:

1840942-13-3

Molecular Weight:

544.94

MDL number:

MFCD34602533

UNSPSC Code:

12352100

NACRES:

NA.12

Assay:

>99% (TLC)

Form:

powder

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Properties

Product Name

C16 Ceramide-d7 (d18:1-d7/16:0), Avanti Research^™ - A Croda Brand 860676P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 mg (860676P-1mg)

manufacturer/tradename

Avanti Research^™ - A Croda Brand 860676P

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCCCCCCCCCC)=O)[C@@](O)([H])/C=C/CCCCCCCCCCC(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H]

InChI

1S/C34H67NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-33(37)32(31-36)35-34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h27,29,32-33,36-37H,3-26,28,30-31H2,1-2H3,(H,35,38)/b29-27+/t32-,33+/m0/s1/i1D3,3D2,5D2

InChI key

YDNKGFDKKRUKPY-HJSOYJPBSA-N

Description

General description

C16 Ceramide (d18:1/16:0) is a synthetic ceramide containing sphingosine with palmitic acid. It is synthesized from ceramide synthase 6 (CerS6). C16 Ceramide-d7 (d18:1-d7/16:0) is a deuterated derivative of ceramide d18:1/16:0.

Application

C16 Ceramide-d7 (d18:1-d7/16:0), has been used as a standard to measure the amount of C16 ceramide in skeletal muscle by liquid chromatography–mass spectrometry (LC-MS).

Biochem/physiol Actions

C16 Ceramide plays a vital role in apoptotic signaling. Examining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma facilitates the prognosis of fatal outcome of coronary artery disease. A newly described and validated liquid chromatography-tandem mass spectrometry methodology uses C16 Ceramide (d18:1/16:0) in a stable isotope form for their clinical-scaled measurement.

Packaging

5 mL Amber Glass Screw Cap Vial (860676P-1mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids

flash_point_f

No data available

flash_point_c

No data available

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