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About This Item
Empirical Formula (Hill Notation):
C42H76D7NO3
CAS Number:
Molecular Weight:
657.16
MDL number:
NACRES:
NA.25
UNSPSC Code:
12352100
Assay:
>99% (TLC)
Form:
powder
Product Name
C24 Ceramide-d7 (d18:1-d7/24:0), Avanti Research™ - A Croda Brand 860678P, powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (860678P-1mg), pkg of 1 × 5 mg (860678P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand 860678P
shipped in
dry ice
storage temp.
−20°C
General description
C24 Ceramide (d18:1/24:0) is a synthetic ceramide containing sphingosine with lignoceric acid. Ceramide synthase 2 is responsible for the synthesis of C24 ceramide. C24 Ceramide-d7 (d18:1-d7/24:0) is a deuterated derivative of C24 Ceramide (d18:1/24:0).
Application
C24 Ceramide-d7 (d18:1-d7/24:0) has been used as a standard in liquid chromatography–mass spectrometry (LC-MS) for quantitative analysis of C24 ceramide in skeletal muscle.
Biochem/physiol Actions
C24 Ceramide plays a vital role in inducing cell death. Altered levels of C24 ceramide might be a potential indication in tumor monitoring. Determining the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios in human plasma helps to predict fatal outcome of coronary artery disease. The stable isotope form of C24 Ceramide (d18:1/24:0) is convenient for a newly described validated liquid chromatography-tandem mass spectrometry methodology for their clinical-scaled measurement.
Packaging
5 mL Amber Glass Screw Cap Vial (860678P-1mg)
5 mL Amber Glass Screw Cap Vial (860678P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
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