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Merck

878120P

Avanti

C18 Lyso PAF

Avanti Research - A Croda Brand

Synonym(s):

1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C26H56NO6P
CAS Number:
Molecular Weight:
509.70
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Product Name

C18 Lyso PAF, Avanti Research - A Croda Brand 878120P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 5 mg (878120P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 878120P

lipid type

bioactive lipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

SMILES string

O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COCCCCCCCCCCCCCCCCCC

InChI

1S/C26H56NO6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-22-31-24-26(28)25-33-34(29,30)32-23-21-27(2,3)4/h26,28H,5-25H2,1-4H3/t26-/m1/s1

InChI key

XKBJVQHMEXMFDZ-AREMUKBSSA-N

General description

C18-lysoPAF, also known as 1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine, is a synthetic lyso-platelet activating factor (PAF). It is a precursor and metabolite of 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (C18:0 PAF). Lyso-platelet activating factor (PAF) is synthesized from PAF acetylhydrolases by the degradation of PAF. Additionally, it is also synthesized in the remodeling pathway from 1-O-alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine (1-alkyl-phosphatidylcholine) by the enzyme phospholipase.

Application

C18-lysoPAF (1-O-octadecyl-2-hydroxy-sn-glycero-3-phosphocholine) has been used to study its effect on human eosinophil degranulation.

Packaging

5 mL Amber Glass Screw Cap Vial (878120P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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