Skip to Content
Merck

05-486

Anti-FADD Antibody, clone 1F7

clone 1F7, Upstate®, from mouse

Synonym(s):

Anti-GIG3, Anti-IMD90, Anti-MORT1

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Anti-FADD Antibody, clone 1F7, clone 1F7, Upstate®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

1F7, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

NM_003824

UniProt accession no.

Q13158

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... FADD(8772)
mouse ... Fadd(14082)

Analysis Note

Control
Positive Antigen Control: Catalog #12-303, Jurkat cell lysate.
routinely evaluated by immunoblot on RIPA lysates from Jurkat cells

Application

Anti-FADD Antibody, clone 1F7 detects level of FADD & has been published & validated for use in WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

FADD

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

28kDa

Immunogen

GST-tagged full-length fusion protein corresponding to human FADD

Other Notes

Replaces: 04-1113

Physical form

Format: Purified
PBS, pH 7.2 and 50% glycerol
Protein A chromatography

Preparation Note

2 years at -20°C

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Simon Thompson et al.
The Journal of biological chemistry, 286(22), 19331-19339 (2011-04-12)
We have previously shown that the cell death-promoting protein Bcl-2-interacting mediator of cell death (Bim) is ubiquitinated and degraded following a neuroprotection-conferring episode of brief ischemia (preconditioning). Here, we identify the E3 ligase that ubiquitinates Bim in this model, using
Death domain mutagenesis of KILLER/DR5 reveals residues critical for apoptotic signaling
McDonald, E. R., 3rd, et al
The Journal of Biological Chemistry, 276, 14939-14945 (2001)
Hayley I Muendlein et al.
Nature communications, 12(1), 86-86 (2021-01-06)
Inflammation and cell death are closely linked arms of the host immune response to infection, which when carefully balanced ensure host survival. One example of this balance is the tightly regulated transition from TNFR1-associated pro-inflammatory complex I to pro-death complex
Prajwal Gurung et al.
Journal of immunology (Baltimore, Md. : 1950), 192(4), 1835-1846 (2014-01-24)
The Nlrp3 inflammasome is critical for host immunity, but the mechanisms controlling its activation are enigmatic. In this study, we show that loss of FADD or caspase-8 in a RIP3-deficient background, but not RIP3 deficiency alone, hampered transcriptional priming and
R K Subbarao Malireddi et al.
ImmunoHorizons, 4(12), 789-796 (2020-12-15)
Bacterial pathogens from the genus Yersinia cause fatal sepsis and gastritis in humans. Innate immune signaling and inflammatory cell death (pyroptosis, apoptosis, and necroptosis [PANoptosis]) serve as a first line of antimicrobial host defense. The receptor-interacting protein kinase 1 (RIPK1)
View All Related Papers

Global Trade Item Number

SKUGTIN
05-48604053252273124

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service