HCCBP1MAG-58K
MILLIPLEX® Human Circulating Cancer Biomarker Panel
Configurable Human Circulating Cancer Biomarker 25-Plex Panel 1
Synonym(s):
human cancer biomarker immunoassay panel, luminex human circulating cancer biomarkers multiplex assay, millipore human circulating cancer biomarkers multiplex kit, Luminex human circulating cancer biomarkers multiplex assay, Millipore human circulating cancer biomarkers multiplex kit
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About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
Product Name
MILLIPLEX® Human Circulating Cancer Biomarker Panel, Configurable Human Circulating Cancer Biomarker 25-Plex Panel 1
species reactivity
human
manufacturer/tradename
Milliplex®
Quality Level
packaging
1 ea of
assay range
accuracy: 35-108%
standard curve range: 0.09-67 mU/mL
(β-HCG)
standard curve range: 0.7-500 pg/mL
(IL-6)
standard curve range: 1.3-1000 pg/mL
(IL-8, TNFα)
standard curve range: 2.7-2000 pg/mL
(TRAIL, TGF-α)
standard curve range: 6.9-5000 pg/mL
(SCF)
technique(s)
multiplexing: suitable
input
serum plasma (Cell culture, cell culture supernatants)
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
Related Categories
Biochem/physiol Actions
Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Preparation Note
Recommended storage for kit components is 2 - 8°C.
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 25 analytes in human serum, plasma, and cell culture supernatants.
Analytes included: α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas (TNFRSF6), sFasL, FGF-2 (FGF-basic), β-HCG (HCGβ), HE4, HGF, IL-6, IL-8 (CXCL8), Leptin, MIF, Osteopontin (OPN), Prolactin, PSA (free)*, PSA (total)*, SCF, TGFα, TNFα, TRAIL (TNFSF10), VEGF
Note: Total PSA and Free PSA cannot be plexed together.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analytes included: α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, CYFRA21-1, sFas (TNFRSF6), sFasL, FGF-2 (FGF-basic), β-HCG (HCGβ), HE4, HGF, IL-6, IL-8 (CXCL8), Leptin, MIF, Osteopontin (OPN), Prolactin, PSA (free)*, PSA (total)*, SCF, TGFα, TNFα, TRAIL (TNFSF10), VEGF
Note: Total PSA and Free PSA cannot be plexed together.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Disclaimer
For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Features and Benefits
- Extensive 25-Plex Analyte Panel: This kit allows for the simultaneous quantification of 25 specific cancer biomarkers, including α-Fetoprotein (AFP), CA125, CA15-3, CA19-9, CEA, and many others, enabling comprehensive cancer analysis.
- Flexible Sample Types: Suitable for human serum, plasma, and tissue/cell culture supernatants or lysates, making it versatile for various research applications.
- Comprehensive Insights into Tumor Biology: By measuring multiple circulating cancer biomarkers simultaneously, researchers can gain deeper insights into tumor dynamics, host response, and the tumor microenvironment.
- Reliable and Accurate Results: The inclusion of internal quality controls and lyophilized standards ensures that assay performance is consistent, leading to trustworthy results.
- User-Friendly Setup: The comprehensive kit contains everything needed for the assay, simplifying the setup process and reducing the likelihood of errors during preparation.
- Enhanced Research Efficiency: The ability to perform multiplex analysis allows for increased throughput, enabling researchers to analyze more samples in less time, which is critical in high-volume research settings.
General description
Circulating cancer biomarkers give insight beyond intracellular oncogenesis and into how the body responds to the presence of a tumor, the dysregulation of homeostasis, and the relationship between a tumor and its environment. Multianalyte panels have become essential tools that enable researchers to measure cancer biomarkers simultaneously, teasing out these relationships and applying them to understand tumor biology.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
Storage Class
10 - Combustible liquids
wgk
WGK 3
Certificates of Analysis (COA)
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Chen-Tzu Chiu et al.
Cancers, 12(6) (2020-06-18)
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A combined blood based gene expression and plasma protein abundance signature for diagnosis of epithelial ovarian cancer--a study of the OVCAD consortium.
Pils, D; Tong, D; Hager, G; Obermayr, E; Aust, S; Heinze, G; Kohl, M; Schuster, E; Wolf et al.
BMC Cancer null
Sandra Tuyaerts et al.
Frontiers in nutrition, 5, 138-138 (2019-01-29)
Curcumin is a botanical with anti-tumor and immunomodulatory properties. We hypothesized that curcumin supplementation might influence inflammatory biomarker levels in endometrial carcinoma (EC). In this open-label, non-randomized phase 2 study (NCT02017353), seven EC patients consumed 2 g/day Curcumin Phytosome (CP)
Jonathan A Kluge et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(21), 5892-5897 (2016-05-11)
Advanced personalized medical diagnostics depend on the availability of high-quality biological samples. These are typically biofluids, such as blood, saliva, or urine; and their collection and storage is critical to obtain reliable results. Without proper temperature regulation, protein biomarkers in
Effect of different exercise modalities plus a hypocaloric diet on inflammation markers in overweight patients: a randomised trial.
Loria-Kohen, V; Fernandez-Fernandez, C; Bermejo, LM; Morencos, E; Romero-Moraleda et al.
Clinical Nutrition (Edinburgh, Scotland) null
Global Trade Item Number
| SKU | GTIN |
|---|---|
| HCCBP1MAG-58K-18 | 04053252803192 |
| HCCBP1MAG-58K-22 | 04053252803239 |
| HCCBP1MAG-58K-04 | 04053252803062 |
| HCCBP1MAG-58K-24 | 04053252803253 |
| HCCBP1MAG-58K-08 | 04053252794025 |
| HCCBP1MAG-58K-10 | 04053252803116 |
| HCCBP1MAG-58K-11 | 04053252803123 |
| HCCBP1MAG-58K-15 | 04053252803161 |
| HCCBP1MAG-58K-16 | 04053252803178 |
| HCCBP1MAG-58K-17 | 04053252803185 |
| HCCBP1MAG-58K-19 | 04053252803208 |
| HCCBP1MAG-58K-20 | 04053252803215 |
| HCCBP1MAG-58K-01 | 04053252803031 |
| HCCBP1MAG-58K-21 | 04053252803222 |
| HCCBP1MAG-58K-02 | 04053252803048 |
| HCCBP1MAG-58K-05 | 04053252803079 |
| HCCBP1MAG-58K-07 | 04053252803093 |
| HCCBP1MAG-58K-03 | 04053252803055 |
| HCCBP1MAG-58K-23 | 04053252803246 |
| HCCBP1MAG-58K-06 | 04053252803086 |
| HCCBP1MAG-58K-09 | 04053252803109 |
| HCCBP1MAG-58K-12 | 04053252803130 |
| HCCBP1MAG-58K-13 | 04053252803147 |
| HCCBP1MAG-58K-14 | 04053252803154 |
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