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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
human
Application:
ELISA, IF, IHC, WB
Technique(s):
ELISA: suitable, immunofluorescence: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable
Citations:
7
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunofluorescence: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable
shipped in
wet ice
Quality Level
Application
Anti-Hepatitis C Virus Antibody, helicase domain NS3 detects level of Hepatitis C Virus & has been published & validated for use in ELISA, IF, WB, IH(P).
ELISA
Immunohistochemistry (Parrafin embedded)
Immunofluorescence
Immunoblot
Final dilutions must be determined by end user
Immunohistochemistry (Parrafin embedded)
Immunofluorescence
Immunoblot
Final dilutions must be determined by end user
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Biochem/physiol Actions
Specific to HCV NS3, helicase domain.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Recombinant protein to NS3
Physical form
Format: Purified
Liquid in PBS, pH 7.4 containing no preservatives
Preparation Note
Store at -20°C in undiluted aliquots for up to 6 months from date of receipt; avoid repeated freeze-thaw cycles; short-term storage (1 week) can be at 2-8°C. Use with sterile tips to prevent contamination.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Jun Zhang et al.
Molecular medicine reports, 12(4), 5109-5115 (2015-07-08)
Chronic hepatitis C virus (HCV) infection is a major cause of hepatocellular carcinoma (HCC) worldwide. The HCV non‑structural protein 3 (NS3) protein is considered to affect normal cellular functions and to be involved in HCV carcinogenesis. The expression of microRNA
Shao-Ru Chen et al.
Molecules (Basel, Switzerland), 21(10) (2016-10-19)
Hepatitis C virus (HCV) infects 200 million people worldwide, and 75% of HCV cases progress into chronic infections, which consequently cause cirrhosis and hepatocellular carcinoma. HCV infection is treated with currently considered standard drugs, including direct anti-viral agents (DAAs), alone
Ming Chen et al.
Microbiology and immunology, 60(6), 407-417 (2016-04-16)
Hepatitis C virus (HCV) non-structural protein 5A (NS5A) is a multifunctional protein that is involved in the HCV life cycle and pathogenesis. In this study, a host protein(s) interacting with NS5A by tandem affinity purification were searched for with the
Rheza Gandi Bawono et al.
The Kobe journal of medical sciences, 67(2), E38-E47 (2021-11-20)
We previously reported that hepatitis C virus (HCV) NS5A (1b, Con1) protein accepts covalent ISG15 conjugation at specific lysine (Lys) residues (K44, K68, K166, K215 and K308), exhibiting proviral effects on HCV RNA replication. Here we investigated a role of
Lin Deng et al.
Journal of virology, 96(6), e0181121-e0181121 (2022-01-20)
We previously reported that hepatitis C virus (HCV) infection activates the reactive oxygen species (ROS)/c-Jun N-terminal kinase (JNK) signaling pathway. However, the roles of ROS/JNK activation in the HCV life cycle remain unclear. We sought to identify a novel role
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB8691 | 04053252660115 |
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