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Merck

222488

N-(1-Naphthyl)ethylenediamine dihydrochloride

ACS reagent grade, >98%, solid

Synonym(s):

2-(1-Naphthylamino)ethylamine dihydrochloride

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About This Item

Linear Formula:
C10H7NHCH2CH2NH2 · 2HCl
CAS Number:
Molecular Weight:
259.17
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
215-981-2
MDL number:
Beilstein/REAXYS Number:
3707471
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Product Name

N-(1-Naphthyl)ethylenediamine dihydrochloride, ACS reagent, >98%

InChI key

MZNYWPRCVDMOJG-UHFFFAOYSA-N

InChI

1S/C12H14N2.2ClH/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12;;/h1-7,14H,8-9,13H2;2*1H

SMILES string

Cl.Cl.NCCNc1cccc2ccccc12

grade

ACS reagent

assay

>98%

form

solid

impurities

≤5% water

mp

194-198 °C (dec.) (lit.)

solubility

H2O: passes test

suitability

passes test for sensitivity to sulfanilamide

functional group

amine

Quality Level

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Application

N-(1-Naphthyl)ethylenediamine dihydrochloride has been used for the preparation of staining solution for the visualization of the reaction product(s) of starch active enzymes, containing α-1, 4 linked and α-1, 6 linked glucose by thin layer chromatography. It has also been used in modified Saville and Griess assays.
N-(1-Naphthyl)ethylenediamine dihydrochloride may be used in the synthesis of 5-[1,2]dithiolan-3-yl-pentanoic acid [2-(naphthalene-1-ylamino)-ethyl]amide (DPAN) by reacting with (±)-1,2-dithiolane-3-pentanoic acid in the presence of N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride and N-hydroxysuccinimide. The solution formed by dissolving N-(1-naphthyl)ethylenediamine dihydrochloride in sulfuric acid-methanol may be used as a reagent for the detection of sugars at nanoscale on thin-layer plates.
Coupling agent for the spectrophotometric determination of aminophenols, phenylenediamines, dinitroanilines, chloroanilines, thiols, and sulfonamides.
Solution of N-(1-naphthyl)ethylenediamine dihydrochloride in sulfuric acid-methanol may be employed for the quantitation of sugars.

General description

N-(1-Naphthyl)ethylenediamine dihydrochloride (NEDA·2HCl) acts as donor molecule and forms charge transfer (CT) complexes with π-acceptors (quinol and picric acid), σ-acceptors (iodine) and vacant orbital acceptors (tin(IV) tetrachloride and zinc chloride). These complexes were investigated by positron annihilation lifetime spectroscopy (PAL).

pictograms

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signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Analytica Chimica Acta, 204, 271-271 (1988)
N-(1-naphthyl)ethylenediamine dihydrochloride as a new reagent for nanomole quantification of sugars on thin-layer plates by a mathematical calibration process.
M Bounias
Analytical biochemistry, 106(2), 291-295 (1980-08-01)
Moamen S Refat et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 122, 34-47 (2013-12-03)
In this work, structural, thermal, morphological, pharmacological screening and positron annihilation lifetime measurements were performed on the interactions between a N-(1-Naphthyl)ethylenediamine dihydrochloride (NEDA·2HCl) donor and three types of acceptors to characterize these CT complexes. The three types of acceptors include
Functionalization of platinum nanoparticles for electrochemical detection of nitrite.
Miao P, et al.
Analytical and Bioanalytical Chemistry, 399(7), 2407-2411 (2011)
Product Analysis of Starch Active Enzymes by TLC.
Cockburn D and Koropatkin N.
Bio-protocol, 5(20) (2015)

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