Skip to Content
Merck

30080

Cysteamine hydrochloride

≥97.0% (RT)

Synonym(s):

β-Mercapto­ethylamine hydrochloride, 2-Amino­ethane­thiol hydrochloride, 2-Mercapto­ethyl­amine hydrochloride, Decarboxy­cysteine hydrochloride, Thio­ethanol­amine hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
HSCH2CH2NH2 · HCl
CAS Number:
156-57-0
Molecular Weight:
113.61
UNSPSC Code:
41106305
NACRES:
NA.51
PubChem Substance ID:
329753425
EC Number:
205-858-1
Beilstein/REAXYS Number:
3590083
MDL number:
MFCD00012904

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Cysteamine hydrochloride, ≥97.0% (RT)

InChI key

OGMADIBCHLQMIP-UHFFFAOYSA-N

InChI

1S/C2H7NS.ClH/c3-1-2-4;/h4H,1-3H2;1H

SMILES string

Cl[H].NCCS

assay

≥97.0% (RT)

form

crystals

mp

64-70 °C
67-71 °C

storage temp.

2-8°C

Quality Level

200

Looking for similar products? Visit Product Comparison Guide

Application

Cysteamine hydrochloride has been used in the in-situ generation of chiral cysteamine-capped cadmium sulfide quantum dots (CA-CdS QDs) for the sensing of Cd2+ and S2-.

Biochem/physiol Actions

Cysteamine hydrochloride is derived from the degradation of coenzyme A endogenously. Its concentration in plasma is low. It is commonly used as a drug for the orphan disease cystinosis, a lysosomal storage disorder, in which cysteamine decreases intralysosomal cystine accumulation.
Cysteamine is an aminothiol that can reduce important oxidized disulfide molecules such as cystine to yield cysteine. Cysteamine is used in a wide range of applications from regulation of gene expression, to depletion of somatostatin, to coating of nanoparticles.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCG0901
BCCF9441
BCCF6297
BCCD5833
BCCD3296

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A circular dichroism sensor for selective detection of Cd2+ and S2- based on the in-situ generation of chiral CdS quantum dots
Sianglam P, et al.
Spectrochemical Analysis by Atomic Absorption and Emission, 183, 408-416 (2017)
Mengxiao Yu et al.
Journal of the American Chemical Society, 133(29), 11014-11017 (2011-07-01)
pH regulates many cellular processes and is also an indicator of disease progression. Therefore, pH-responsive materials often serve as either tools in the fundamental understanding of cell biology or medicine for disease diagnosis and therapy. While gold nanoparticles have broad
Martine Besouw et al.
Drug discovery today, 18(15-16), 785-792 (2013-02-19)
Cysteamine is an amino thiol with the chemical formula HSCH2CH2NH2. Endogenously, cysteamine is derived from coenzyme A degradation, although its plasma concentrations are low. Most experience with cysteamine as a drug originates from the field of the orphan disease cystinosis
Leonid Andronov et al.
Nature communications, 10(1), 4436-4436 (2019-10-02)
CENP-A is an essential histone H3 variant that epigenetically marks the centromeric region of chromosomes. Here we show that CENP-A nucleosomes form characteristic clusters during the G1 phase of the cell cycle. 2D and 3D super-resolution microscopy and segmentation analysis
Paula Díez et al.
Analytical and bioanalytical chemistry, 405(11), 3773-3781 (2012-10-24)
Cysteamine core polyamidoamine G-4 dendron branched with β-cyclodextrins was chemisorbed on the surface of Au electrodes and further coated with Pt nanoparticles. Adamantane-modified glucose oxidase was subsequently immobilized on the nanostructured electrode surface by supramolecular association. This enzyme electrode was
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service