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Merck

31738

Sulfapyridine

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-[2-pyridyl]benzene sulfonamide, N1-(Pyridin-2-yl)sulfanilamide

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About This Item

Empirical Formula (Hill Notation):
C11H11N3O2S
CAS Number:
144-83-2
Molecular Weight:
249.29
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753911
EC Number:
205-642-7
Beilstein/REAXYS Number:
222065
MDL number:
MFCD00038036

Key Documents

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InChI key

GECHUMIMRBOMGK-UHFFFAOYSA-N

InChI

1S/C11H11N3O2S/c12-9-4-6-10(7-5-9)17(15,16)14-11-3-1-2-8-13-11/h1-8H,12H2,(H,13,14)

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2ccccn2

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

Quality Level

100

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General description

Chemical structure: sulfonamide
Sulfapyridine is a metabolite of Sulfasalazine. It is an antibiotic and is mostly used in treating rheumatoid arthritis.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfapyridine (SPY) has been used as internal standard in HPLC method for determination of sulfonamides residue from honey samples.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H361fd

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 2

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK3249
BCCF2670
BCBZ7545
BCBR9634V

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A reliable high-performance liquid chromatography with ultraviolet detection for the determination of sulfonamides in honey.
Granja RH
Analytica Chimica Acta, 613(1), 116-119 (2008)
Fátima Fernández et al.
Biosensors & bioelectronics, 26(4), 1231-1238 (2010-07-20)
Techniques for immunosensing like surface plasmon resonance (SPR) may respond to the need for rapid screening methods to improve food safety. This paper describes the development of a novel portable six channel SPR biosensor based on the plasmon of gold
Cemalettin Alp et al.
Journal of enzyme inhibition and medicinal chemistry, 27(6), 818-824 (2011-12-23)
The inhibition of two human cytosolic carbonic anhydrase (hCA, EC 4.2.1.1) isozymes I, II and human serum isozyme VI, with a series of tosylited aromatic amine derivatives was investigated. The K(I) ranges of compounds 1-14 and acetazolamide against hCA I
Christopher Chidley et al.
Nature chemical biology, 7(6), 375-383 (2011-04-19)
We introduce an approach for detection of drug-protein interactions that combines a new yeast three-hybrid screening for identification of interactions with affinity chromatography for their unambiguous validation. We applied the methodology to the profiling of clinically approved drugs, resulting in
Hai Haham et al.
Environmental science & technology, 46(21), 11870-11877 (2012-10-02)
Sorption-desorption behavior of sulfapyridine was studied with three distinct soil types low in organic carbon with or without the introduction of exogenous dissolved organic matter (DOM). Experiments with bulk soils yielded sorption coefficients equivalent to those obtained with soils richer
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