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Merck

319236

Phenolphthalein solution

0.5 wt. % in ethanol: water (1:1)

Synonym(s):

C20H14O4; Phthalin;3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one

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About This Item

Empirical Formula (Hill Notation):
C20H14O4
CAS Number:
77-09-8
Molecular Weight:
318.32
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24859151
MDL number:
MFCD00005913
Beilstein/REAXYS Number:
284423

Key Documents

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Product Name

Phenolphthalein solution, 0.5 wt. % in ethanol: water (1:1)

InChI

1S/C20H14O4/c21-15-9-5-13(6-10-15)20(14-7-11-16(22)12-8-14)18-4-2-1-3-17(18)19(23)24-20/h1-12,21-22H

SMILES string

Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4

InChI key

KJFMBFZCATUALV-UHFFFAOYSA-N

form

liquid

concentration

0.5 wt. % in ethanol: water (1:1)

technique(s)

titration: suitable

color

colorless

visual transition interval

8.0-10, colorless to red

mp

-35 °C

density

0.918 g/mL at 25 °C

λmax

552 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

Quality Level

200

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Application

Phenolphthalein solution has been used to measure total titratable acids by titration method.

General description

Phenolphthalein is an acid base indicator. It is a weak acid, which is colorless in acidic solution and turns puce pink in alkaline solution. Phenolphthalein is genotoxic. It might cause oxidative damage and binds to estrogen receptors.
Phenolphthalein solution is a synthetic indicator. It is colorless in acidic and neutral conditions. Phenolphthalein gives pink color when added to a base, therefore it is considered as a base indicator.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

hcodes

H226,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

75.2 °F - closed cup

flash_point_c

24 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

77-09-8

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG9904
MKCN1905
STBJ5862
MKCG8815
STBH7331

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Charu Maini
Headstart Science (CCE), 7 (2017)
Cytokinin Treatment Modifies Litchi Fruit Pericarp Anatomy Leading to Reduced Susceptibility to Post-harvest Pericarp Browning
Fahima A, et al.
Plant Science (2019)
Phenolphthalein laxatives and risk of cancer
Coogan PF, et al.
Journal of the National Cancer Institute, 92(23), 1943-1944 (2000)
Physical Chemistry: Understanding our Chemical World (2008)
Amit Fahima et al.
Plant science : an international journal of experimental plant biology, 283, 41-50 (2019-05-28)
Litchi (Litchi chinensis Sonn.) is a subtropical fruit known for its attractive red pericarp color, semi-translucent white aril and unique flavor and aroma. Rapid post-harvest pericarp browning strictly limits litchi fruit marketing. In the current research, we hypothesized that modification
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