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About This Item
Empirical Formula (Hill Notation):
C9H11NO2
CAS Number:
Molecular Weight:
165.19
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
638434
InChI
1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3
SMILES string
CCOC(=O)c1ccc(N)cc1
InChI key
BLFLLBZGZJTVJG-UHFFFAOYSA-N
grade
pharmaceutical primary standard
API family
benzocaine
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
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Application
Benzocaine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Other Notes
Sales restrictions may apply.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
233.6 °F
flash_point_c
112 °C
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L A Linares et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 18(3), 267-269 (1990-07-01)
Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and
Methemoglobinemia: a complication after fiberoptic orotracheal intubation with benzocaine spray. A case report.
F D Ellis et al.
The Journal of bone and joint surgery. American volume, 77(6), 937-939 (1995-06-01)
H A Cooper
Southern medical journal, 90(9), 946-948 (1997-09-26)
Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray
Ahmed Dahshan et al.
Pediatrics, 117(4), e806-e809 (2006-04-06)
Severe methemoglobinemia resulting from the use of topical benzocaine has been reported in adults as a rare complication. Here we report a case of severe acquired methemoglobinemia resulting from topical use of benzocaine spray during diagnostic upper gastrointestinal endoscopy in
Daniel D Moos et al.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates, 30(5), 342-345 (2007-12-01)
Benzocaine administration to facilitate upper endoscopic procedures can result in the relatively uncommon but potentially fatal complication known as methemoglobinemia. For this reason, the Veterans Health Administration (VA) announced on February 8, 2006, that they would stop using benzocaine-containing sprays
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