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About This Item
Empirical Formula (Hill Notation):
C20H24N2 · C4H4O4
CAS Number:
Molecular Weight:
408.49
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24
SMILES string
N(CCC1=C(c3c(cccc3)C1)C(C)c2ncccc2)(C)C.OC(=O)\C=C/C(=O)O
InChI
1S/C20H24N2.C4H4O4/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20;5-3(6)1-2-4(7)8/h4-10,12,15H,11,13-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
SWECWXGUJQLXJF-BTJKTKAUSA-N
grade
pharmaceutical primary standard
API family
dimetindene
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Dimetindene maleate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Anaphylactic shock caused by buffalo's mozzarella cheese.
Sigrid M C Broekaert et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 101(1), 105-107 (2008-08-07)
V K Kouritas et al.
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 45(2), 113-119 (2010-10-01)
To investigate whether surgical trauma in a rabbit adhesion formation model and the administration of normal saline (N/S), icodextrin (ID) and/or dimetindene maleate (DM) changes the permeability of the normal rabbit parietal peritoneum. A total of 45 female rabbits were
Wilna J Moree et al.
Journal of medicinal chemistry, 52(17), 5307-5310 (2009-08-12)
Analogues of the known H(1)-antihistamine R-dimethindene were profiled as potential agents for the treatment of insomnia. Several highly selective compounds were efficacious in rodent sleep models. On the basis of overall profile, indene 1d and benzothiophene 2a had pharmacokinetic properties
P Mikus et al.
Die Pharmazie, 62(1), 31-33 (2007-02-14)
Cyclodextrin-mediated capillary zone electrophoresis in a hydrodynamically closed separation system with suppressed electroosmotic flow and UV absorbance photometric detection was developed for a high effective separation and quantitation of dimethindene enantiomers in various pharmaceutical formulations (solution, gel, capsules). The running
[Aso an inspection of the family dog is warrented here].
M F Nentwich et al.
MMW Fortschritte der Medizin, 148(42), 5-5 (2007-07-12)
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