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Merck

Z2251

Zinquin ethyl ester

≥95% purity (HPLC), solid

Synonym(s):

2-Methyl-8-[(4-methylphenyl)sulfonylamino]-6-(ethyloxycarbonylmethyloxy)quinoline

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About This Item

Empirical Formula (Hill Notation):
C21H22N2O5S
Molecular Weight:
414.47
UNSPSC Code:
12171500
PubChem Substance ID:
329831605
NACRES:
NA.47
MDL number:
MFCD00797629

Key Documents

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Product Name

Zinquin ethyl ester, ≥95% (HPLC), solid

SMILES string

CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c3nc(C)ccc3c1

InChI

1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3

InChI key

KCASTCXJTDRDFT-UHFFFAOYSA-N

assay

≥95% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble
methanol: soluble

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

Related Categories

Biochem/physiol Actions

Used to detect zinc in cells by UV fluorescence.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCP9144
MKCM8643
MKCM1106
MKCL1265
MKCF2854

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Journal of applied toxicology : JAT, 37(8), 895-901 (2016-11-20)
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Abrogation of Nuclear Factor-?B Activation Is Involved in Zinc Inhibition of Lipopolysaccharide-Induced Tumor Necrosis Factor-a Production and Liver Injury
Zhanxiang Z
The American Journal of Pathology (2004)
Chris D
Reviews in Fluorescence (2012)
High-Affinity Zn2+ Uptake System ZnuABC Is Required for Bacterial Zinc Homeostasis in Intracellular Environments and Contributes to the Virulence of Salmonella enterica?
Serena A
Infection and Immunity (2007)
Phuong Kim To et al.
International journal of molecular sciences, 19(10) (2018-10-10)
The prostate gland contains a high level of intracellular zinc, which is dramatically diminished during prostate cancer (PCa) development. Owing to the unclear role of zinc in this process, therapeutic applications using zinc are limited. This study aimed to clarify
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