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About This Item
Linear Formula:
(CH3)2SO
CAS Number:
Molecular Weight:
78.13
UNSPSC Code:
12191502
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
Assay:
≥99.9%
Grade:
ACS reagent
Vapor pressure:
0.42 mmHg ( 20 °C)
InChI key
IAZDPXIOMUYVGZ-UHFFFAOYSA-N
InChI
1S/C2H6OS/c1-4(2)3/h1-2H3
SMILES string
CS(C)=O
grade
ACS reagent
Quality Level
vapor pressure
0.42 mmHg ( 20 °C)
assay
≥99.9%
form
liquid
autoignition temp.
573 °F
expl. lim.
42 %, 63 °F
dilution
(for analytical testing)
impurities
≤0.001 meq/g Titr. acid, ≤0.1% water
evapn. residue
≤0.01%
color
clear colorless
density
1.10 g/mL (lit.)
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General description
Dimethyl sulfoxide is an organosulfur, commonly used as a polar solvent that can dissolve a wide range of polar and non-polar compounds. It is also utilized as a reaction reagent in several well-known processes, including swern oxidation, 2a pfitzner-moffatt oxidation, 2b, and the corey-chaykovsky reaction.
Our premium ACS solvents are ideal for routine chemical synthesis, drying, purification, and critical labware cleaning. They meet or exceed the rigorous standards of the American Chemical Society (ACS), ensuring high-quality results for your research needs.
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Premium ACS Solvents: Our solvents meet or exceed the stringent standards set by the American Chemical Society, ensuring high quality and reliability for your laboratory applications.
Replicable and Publishable Results: Designed for consistency, our solvents deliver results that can be reliably reproduced, making them ideal for research that requires publication.
Versatile Applications: Suitable for routine chemical synthesis, drying, purification, and critical labware cleaning, our solvents cater to a wide range of research needs in the laboratory.
Application
Dimethyl sulfoxide (DMSO) has been used:
- in the preparation of ethyl 4-[18F]fluorobenzoate.
- in the culture medium for 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) assay.
- as a solvent in chemical synthesis.
- to dissolve and prepare stock solutions of small molecules, drugs, and chemical compounds for various assays and experiments.
Other Notes
For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table
Dimethyl Sulfoxide Miscibility/Immiscibility Table
Disclaimer
Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
188.6 °F - closed cup
flash_point_c
87 °C - closed cup
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Shuang Hou et al.
Journal of visualized experiments : JoVE, (52)(52), doi:10-doi:10 (2011-07-07)
Biomolecules, including peptides¹⁻⁹, proteins¹⁰⁻¹¹, and antibodies and their engineered fragments¹²⁻¹⁴, are gaining importance as both potential therapeutics and molecular imaging agents. Notably, when labeled with positron-emitting radioisotopes (e.g., Cu-64, Ga-68, or F-18), they can be used as probes for targeted
P Roy et al.
The FEBS journal, 277(2), 441-452 (2009-12-18)
EVI1 is a nuclear zinc finger protein essential to normal development, which participates in acute myeloid leukaemia progression and transforms Rat1 fibroblasts. In this study we show that enforced expression of Evi1 in Rat1 fibroblasts protects from paclitaxel-induced apoptosis, consistent
A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE.
S HAKOMORI
Journal of biochemistry, 55, 205-208 (1964-02-01)
Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.
Omura K and Swern D.
Tetrahedron, 34(11), 1651-1660 (1978)
Amino acid analysis: aqueous dimethyl sulfoxide as solvent for the ninhydrin reaction.
S Moore
The Journal of biological chemistry, 243(23), 6281-6283 (1968-12-10)
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