Skip to Content
Merck

B3501

Betaine hydrochloride

synthetic (organic), ≥99%, osmoprotectant, powder or crystals

Synonym(s):

(Carboxymethyl)trimethylammonium hydrochloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
(CH3)3N+CH2COOH · Cl-
CAS Number:
590-46-5
Molecular Weight:
153.61
NACRES:
NA.77
PubChem Substance ID:
24278266
UNSPSC Code:
12352202
EC Number:
209-683-1
MDL number:
MFCD00011903
Beilstein/REAXYS Number:
3916181

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Betaine hydrochloride, ≥99%

InChI key

HOPSCVCBEOCPJZ-UHFFFAOYSA-N

InChI

1S/C5H11NO2.ClH/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H

SMILES string

[Cl-].C[N+](C)(C)CC(O)=O

biological source

synthetic (organic)

assay

≥99%

form

powder or crystals

mp

241-242 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless

storage temp.

room temp

Quality Level

100

Gene Information

human ... BHMT(635), BHMT2(23743)

Looking for similar products? Visit Product Comparison Guide

Application

Betaine hydrochloride has been used as a component of fixative in HEPES or cacodylate buffer to improve preservation of the ultrastructural morphology of human spermatozoa.

Biochem/physiol Actions

Betaine hydrochloride can decrease hepatotoxicity, that is stimulated by ethanol.
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

General description

Betaine (trimethyl glycine) is an osmoprotectant, which is highly effective than proline. It is formed in from choline. Betaine is usually present in grains, spinach, beets, broccoli, shellfish and marine algae.

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H318

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
MKCQ7711
MKCQ2275
MKCN9498
MKCM6781
MKCK5404

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Can Phytochemicals be Effective in Preventing Ethanol-Induced Hepatotoxicity in the Geriatric Population? An Evidence-Based Revisit
Foods and Dietary Supplements in the Prevention and Treatment of Disease in Older Adults, 163-170 (2015)
Improved preservation of ultrastructural morphology in human spermatozoa using betaine in the primary fixative
Swan MA
International Journal of Andrology, 20(1), 45- 54 (1997)
Effect of drying medium on the viability of dried
Selmer OE, et al.
Immobilized Cells: Basics and Applications, 11, 229-229 (1996)
Noha H Youssef et al.
The ISME journal, 8(3), 636-649 (2013-09-21)
We investigated the mechanisms of osmoadaptation in the order Halobacteriales, with special emphasis on Haladaptatus paucihalophilus, known for its ability to survive in low salinities. H. paucihalophilus genome contained genes for trehalose synthesis (trehalose-6-phosphate synthase/trehalose-6-phosphatase (OtsAB pathway) and trehalose glycosyl-transferring
Jun Cao et al.
Journal of biomedical nanotechnology, 9(11), 1847-1861 (2013-09-26)
pH-sensitive micelles are considered promising carriers for tumor targeted drug delivery. In this study, novel pH-sensitive star-shape copolymers of amphiphilic poly(epsilon-caprolactone)-b-poly(N, N-diethylaminoethyl methacrylate)-r-poly(N-(3-sulfopropyl)-N-methacryloxyethy-N, N-diethylammoniumbetaine) (4sPCLDEAS) are designed and synthesized with the combination of ring opening polymerization (ROP) and atom radical
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service