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Merck

C1426

Cesium methanesulfonate

used in patch clamp techniques

Synonym(s):

CsMSF, CsMeS, Methanesulfonic acid cesium salt

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About This Item

Linear Formula:
CH3O3SCs
CAS Number:
2550-61-0
Molecular Weight:
228.00
NACRES:
NA.25
PubChem Substance ID:
24892412
UNSPSC Code:
12161700
MDL number:
MFCD00075523
Form:
powder

Key Documents

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Product Name

Cesium methanesulfonate, used in patch clamp techniques

InChI

1S/CH4O3S.Cs/c1-5(2,3)4;/h1H3,(H,2,3,4);/q;+1/p-1

SMILES string

[Cs+].CS([O-])(=O)=O

InChI key

DJKJXRLREATOMF-UHFFFAOYSA-M

form

powder

mp

262-264 °C (lit.)

Quality Level

100

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Application

Cesium methanesulfonate has been used as a supplement in intracellular solution for the patch clamp recording system.

General description

Cesium methanesulfonate is used as a component of intracellular recording solutions of electrodes for patch clamp techniques in cell electrophysiology studies. Cesium methanesulfonate is used as an current carrier as cesium acts as a potassium (K+) channel blocker, while methanesulfonate is not transported through chloride (Cl-) channels.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN9025
MKCM3250
MKCH9002
MKCF0041
MKBX6613V

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An optogenetics- and imaging-assisted simultaneous multiple patch-clamp recording system for decoding complex neural circuits.
Wang G
Nature Protocols, 10, 397-397 (2015)
P L Li et al.
American journal of physiology. Heart and circulatory physiology, 280(1), H208-H215 (2000-12-21)
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The Journal of Neuroscience, 24, 2871-2879 (2010)
Samir Haj-Dahmane et al.
The Journal of pharmacology and experimental therapeutics, 331(1), 186-196 (2009-07-14)
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M Ouardouz et al.
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Whole cell recordings were used in hippocampal slices of young rats to examine unitary inhibitory postsynaptic currents (uIPSCs) evoked in CA1 pyramidal cells at room temperature. Loose cell-attached stimulation was applied to activate single interneurons of different subtypes located in
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