F1506
Sodium fumarate dibasic
≥99%
Synonym(s):
Disodium fumarate, Fumaric acid disodium salt
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About This Item
Linear Formula:
NaOOCCH=CHCOONa
CAS Number:
Molecular Weight:
160.04
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
241-087-7
Beilstein/REAXYS Number:
4301302
MDL number:
Product Name
Sodium fumarate dibasic, ≥99%
InChI key
MSJMDZAOKORVFC-SEPHDYHBSA-L
InChI
1S/C4H4O4.2Na/c5-3(6)1-2-4(7)8;;/h1-2H,(H,5,6)(H,7,8);;/q;2*+1/p-2/b2-1+;;
SMILES string
[Na+].[Na+].[O-]C(=O)\C=C\C([O-])=O
assay
≥99%
Quality Level
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Application
- Enhancement of drug absorption: Sodium fumarate dibasic is utilized to improve the dissolution behavior and oral absorption of drugs with pH-dependent solubility, enhancing bioavailability and therapeutic efficacy in pharmaceutical applications (Salehi et al., 2021).
- Development of novel drug carriers: The compound is used in the synthesis and characterization of novel injectable drug carriers, aiming to enhance the delivery and efficacy of therapeutic agents in medical treatment strategies (Guo et al., 2005).
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Xueying Liu et al.
Molecules (Basel, Switzerland), 24(12) (2019-06-21)
The major objective of this study was to investigate the anti-chronic nonbacterial prostatitis (CNP) mechanism of T. patula by metabolomics and network pharmacology. The study demonstrated that the flavonoids and polysaccharides of T. patula could alleviate prostatitis by improving the
Wei Jin et al.
Current microbiology, 74(11), 1337-1342 (2017-08-02)
The effect of disodium fumarate (DF) on the ruminal fermentation profiles, the accumulation of lipopolysaccharide (LPS) and bioamines, and the composition of the ruminal bacterial community was investigated by in vitro rumen fermentation. The addition of DF increased the total
Miaomiao Jiang et al.
Scientific reports, 7(1), 8739-8739 (2017-08-20)
Metabonomics/metabolomics is a rapid technology for comprehensive profiling of small molecule metabolites in cells, tissues, or whole organisms, the application of which has led to understanding pathophysiologic mechanisms of cardiometabolic diseases, defining predictive biomarkers for those diseases, and also assessing
Yasemin D Yilmazel et al.
Bioelectrochemistry (Amsterdam, Netherlands), 119, 142-149 (2017-10-11)
Few microorganisms have been examined for current generation under thermophilic (40-65°C) or hyperthermophilic temperatures (≥80°C) in microbial electrochemical systems. Two iron-reducing archaea from the family Archaeoglobaceae, Ferroglobus placidus and Geoglobus ahangari, showed electro-active behavior leading to current generation at hyperthermophilic
Carl Roos et al.
Molecular pharmaceutics, 14(12), 4252-4261 (2017-09-19)
Currently, the screening of new drug candidates for intestinal permeation is typically based on in vitro models which give no information regarding regional differences along the gut. When evaluation of intestinal permeability by region is undertaken, two preclinical rat models
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