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Merck

L5777

N-Lauroylsarcosine sodium salt

BioXtra, ≥97% (TLC)

Synonym(s):

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
57654332
EC Number:
205-281-5
Beilstein/REAXYS Number:
5322974
MDL number:
MFCD00042728

Key Documents

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Product Name

N-Lauroylsarcosine sodium salt, BioXtra, ≥97% (TLC)

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

description

anionic

product line

BioXtra

assay

≥97% (TLC)

form

powder

mol wt

micellar avg mol wt 600
average mol wt 600

aggregation number

2

impurities

≤0.1% Insoluble matter
≤0.1% Phosphorus (P)

CMC

14.6 mM (20-25°C)

solubility

H2O: 0.1 M, clear, colorless to very faintly yellow

density

(1,14 g/cm3 at 20 °C )

cation traces

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.005%
K: ≤0.01%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.01%
Zn: ≤0.0005%

Quality Level

200

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Application

N-Lauroylsarcosine sodium salt has been used in a study to assess involvement of histamine released from epidermal keratinocytes. It has also been used in a study to develop a simple method for extracting DNA from Cryptosporidium oocysts.

General description

N-Lauroylsarcosine sodium salt is an anionic surfactant.

Other Notes

Anionic surfactant.

pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 1

flash_point_f

512.6 °F - closed cup

flash_point_c

267 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL0595
SLCD8078
SLCC5819
SLCB4258
SLCB5541

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Takahiro Sekikawa et al.
New biotechnology, 29(1), 139-143 (2011-09-20)
Detection of low amounts of Cryptosporidium oocysts in raw water sources is considered an important component in the management, prevention and control of Cryptosporidium in drinking water supplies as Cryptosporidium causes massive waterborne outbreaks worldwide. As Cryptosporidium has a robust
Yoshihiro Inami et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(11), 1225-1230 (2012-11-06)
The primary function of surfactants is to remove dirt, exfoliated corneum cells, and microorganisms from the skin. However, the use of toiletries such as soaps and shampoos containing surfactants may cause adverse effects such as cutaneous irritation, dryness, and itching.
Gültekin Tamgüney et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(35), 15002-15006 (2009-08-27)
Prions are infectious proteins that cause fatal neurodegenerative diseases. Because astrocytic gliosis marked by the deposition of fibrils composed of GFAP is a prominent feature of prion disease, we asked whether GFAP might be used as a surrogate marker for
Linda A Terry et al.
Veterinary research, 42, 65-65 (2011-05-20)
Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence from animal models has implicated urine, blood, saliva, placenta and faeces as possible sources of the infection.
Sang Su Kwak et al.
Nature communications, 11(1), 1377-1377 (2020-03-15)
The relationship between amyloid-β (Aβ) species and tau pathology in Alzheimer's disease (AD) is not fully understood. Here, we provide direct evidence that Aβ42/40 ratio, not total Aβ level, plays a critical role in inducing neurofibrillary tangles (NTFs) in human
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