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Merck

L7414

N-Lauroylsarcosine sodium salt solution

Molecular Biology, 20%

Synonym(s):

Sarcosyl, Sarkosyl NL, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosinate solution

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
137-16-6
Molecular Weight:
293.38
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
24896478
MDL number:
MFCD00042728
Beilstein/REAXYS Number:
5322974

Key Documents

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Product Name

N-Lauroylsarcosine sodium salt solution, Molecular Biology, 20%

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

biological source

plant

grade

Molecular Biology

description

anionic

assay

19-21%

form

liquid

mol wt

293.38 g/mol

concentration

19-21% (Titration by HClO4)
20%

solubility

water: soluble at 20 °C

foreign activity

DNase, RNase, and protease, none detected

Quality Level

200

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Application

N-Lauroylsarcosine sodium salt has been used in a study to assess the mechanisms underlying surfactant-induced itching. It has also been used in a study to investigate the formation of pH-responsive, stable vesicles resulting from an interaction with N-cetylpyridinium chloride (CPC) and N-dodecylpyridinium chloride (DPC) in aqueous mixtures.

Features and Benefits

N-Lauroylsarcosine does not precipitate and is commonly used in place of SDS.

General description

N-Lauroylsarcosine sodium salt solution is an anionic surfactant which can be used in DNA extraction.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

512.6 °F

flash_point_c

267 °C

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Certificates of Analysis (COA)

Lot/Batch Number
SLCL3314
SLCK9408
SLCK2329
SLCJ7399
SLCH6689

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Interaction of sodium N-lauroylsarcosinate with N-alkylpyridinium chloride surfactants: Spontaneous formation of pH-responsive, stable vesicles in aqueous mixtures
Ghosh, S. and J. Dey
Journal of Colloid and Interface Science, 358, 9-9 (2011)
Emanuele Gabellieri et al.
European journal of medicinal chemistry, 204, 112615-112615 (2020-08-11)
The compound screening was initiated with a direct staining assay to identify compounds binding to Tau aggregates and not Abeta plaques using human brain sections derived from late stage Alzheimer's disease donors. The binding of Tau aggregate selective compounds was
Luoquan Li et al.
ACS sensors, 4(5), 1299-1305 (2019-05-03)
Droplet microfluidics-based platform (Drop-seq) has been shown to be a powerful tool for single cell expression profiling. Nevertheless, this platform required the simultaneous encapsulation of single cell and single barcoded bead, the incidence of which was very low, limiting its
Takahiro Sekikawa et al.
New biotechnology, 29(1), 139-143 (2011-09-20)
Detection of low amounts of Cryptosporidium oocysts in raw water sources is considered an important component in the management, prevention and control of Cryptosporidium in drinking water supplies as Cryptosporidium causes massive waterborne outbreaks worldwide. As Cryptosporidium has a robust
Yoshihiro Inami et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(11), 1225-1230 (2012-11-06)
The primary function of surfactants is to remove dirt, exfoliated corneum cells, and microorganisms from the skin. However, the use of toiletries such as soaps and shampoos containing surfactants may cause adverse effects such as cutaneous irritation, dryness, and itching.
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