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6.18030

Acetonitrile

Synonym(s):

Methyl cyanide, Anhydrous ACN, Dry MeCN

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About This Item

Linear Formula:
CH3CN
CAS Number:
75-05-8
Molecular Weight:
41.05
UNSPSC Code:
12191502
Beilstein/REAXYS Number:
741857
MDL number:
MFCD00001878
Assay:
≥99.8% (GC)
Technique(s):
HPLC: suitable
Bp:
81-82 °C (lit.)
Vapor pressure:
72.8 mmHg ( 20 °C)
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Quality Level

100

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

assay

≥99.8% (GC)

form

liquid

autoignition temp.

973 °F

expl. lim.

16 %

technique(s)

HPLC: suitable

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

solubility

water: soluble (1,000 g/l at 25 °C (77 °F))

density

0.786 g/mL at 25 °C (lit.)

suitability

suitable for chromatography

application(s)

general analytical

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

General description

Acetonitrile is a highly polar, aprotic solvent known forits excellent ability to dissolve a wide range of analytes. It is commonly usedin reversed-phase HPLC due to its low viscosity and high purity, which enhancecolumn efficiency and resolution.Supelco® is a leading provider of high-quality HPLC solvents, targeting laboratories inthe pharmaceutical, environmental, and food safety sectors. The brand isrecognized for its commitment to precision, reliability, and innovation inanalytical chemistry. Supelco®′s extensive range of solvents ensures optimalperformance and reproducibility, making it a preferred choice for professionalsseeking consistent and accurate analytical results.

Application

  • Gradient Elution: Ideal for gradient elution techniques, enhancing the resolution and separation efficiency of complex mixtures.
  • Pharmaceutical Analysis: Frequently employed in the analysis of active pharmaceutical ingredients (APIs) and their impurities, ensuring compliance with regulatory standards.
  • Biological Sample Analysis: Used for the analysis of proteins, peptides, and metabolites in biological samples, facilitating accurate quantification and identification.
  • Environmental Monitoring: Applied in the HPLC analysis of environmental samples to detect and quantify contaminants in water, soil, and air.

Features and Benefits

  • High Purity: Formulated with minimal impurities, ensuring reliable and reproducible results essential for sensitive analytical applications.
  • Excellent UV Transparency: Provides optimal UV transmittance, facilitating accurate detection and enhancing sensitivity in HPLC analyses.
  • Low Evaporation Residue: Minimizes contamination risk, leading to cleaner separations and improved analytical reliability.
  • Batch-to-Batch Consistency: Ensures uniform quality and performance across different production batches, enhancing reproducibility and confidence in analytical results.

Legal Information

Supelco is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

flash_point_f

35.6 °F - closed cup

flash_point_c

2.0 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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