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About This Item
UNSPSC Code:
41104923
NACRES:
NB.22
eCl@ss:
32039006
Material:
flat bottom wells, Durapore PVDF membrane, clear acrylic plate
Pore size:
0.45 μm pore size
Sterility:
non-sterile
Binding type:
high binding surface
Quality Segment
material
flat bottom wells, Durapore PVDF membrane, clear acrylic plate
description
This clear 96 well filter plate has a Hydrophobic PVDF membrane used for PAMPA., without underdrain
sterility
non-sterile
usage
Manual
feature
hydrophobic, lid
packaging
pkg of 10 plates
manufacturer/tradename
MultiScreen®
technique(s)
cell based assay: suitable, dot blot: suitable, parallel artificial membrane permeation assay (PAMPA): suitable
plate size
96 wells
well maximum volume
300 μL
working volume
50-250 μL
matrix
Immobilon®-P
pore size
0.45 μm pore size
binding type
high binding surface
compatibility
manifold only
shipped in
ambient
storage temp.
no temp limit
General description
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.
Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput
Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1
PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3
MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
Filter Code: IP
Application
Research Category
Assays
Protein
Assays
Protein
Physical form
Color Code: Clear
Other Notes
Automation Compatible: No
Legal Information
Immobilon is a registered trademark of Merck KGaA, Darmstadt, Germany
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
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