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About This Item
UNSPSC Code:
41104923
NACRES:
NB.22
eCl@ss:
32039006
Material:
clear polystyrene plate, flat bottom wells, polycarbonate membrane
Pore size:
5 μm pore size
Sterility:
sterile
Binding type:
Tissue Culture (TC)-treated surface
Quality Segment
material
clear polystyrene plate, flat bottom wells, polycarbonate membrane
description
Clear, Sterile, 5.0 µm pore size, Polycarbonate (PC) membrane, 10 plates
sterility
sterile
usage
Manual
feature
hydrophilic, lid
packaging
pkg of 10 plates
manufacturer/tradename
MultiScreen®
technique(s)
DNA purification: suitable, cell based assay: suitable, cell migration: suitable
filtration area
0.28 cm2
plate size
96 wells
well maximum volume
350 μL
working volume
50-250 μL
pore size
5 μm pore size
binding type
Tissue Culture (TC)-treated surface
compatibility
manifold only
shipped in
ambient
storage temp.
10-30°C
General description
The MultiScreen®-MIC (Migration, Invasion, Chemotaxis) plate is a 96-well disposable device for use in functional assays for screening protein libraries and compound leads for drug discovery. It is designed to support high throughput cell-based functional assays such as migration, invasion, and chemotaxis with suspension and/or adherent cell lines, using a single device. The plates can be used to perform and quantify cell migration or invasion across coated or uncoated membranes in response to a concentration gradient. The MultiScreen-MIC plates are available in several pore sizes to accommodate MIC assays with a variety of cell lines and are intended for single use only.
Application
MultiScreen® Migration Invasion and Chemotaxis Filter Plate, 96 well has been used in the transwell/cellular migration assay using:
- interleukin (IL)-4- and IL-12-treated T cells
- THP-1 (human acute monocytic leukemia cell line)
- in vitro activated, purified and IL-2-maintained galectin-3-deficient (gal3)-/- and gal3+/+ cluster of differentiation 4 (CD4)+ OTII T cells
Legal Information
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
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