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MPC4NTR10

Multiscreen® 96 well Plate, polycarbonate membrane

pore size 0.45 μm, non-sterile

Synonym(s):

96-Well Plate

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About This Item

UNSPSC Code:
41104923
NACRES:
NB.22
eCl@ss:
32039006
Material:
clear polystyrene plate, flat bottom wells, polycarbonate membrane
Pore size:
0.45 μm pore size
Sterility:
non-sterile
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Quality Segment

400

material

clear polystyrene plate, flat bottom wells, polycarbonate membrane

description

This 96-well filter plate has a Polycarbonate membrane used for Permeability studies.

sterility

non-sterile

usage

Manual

feature

hydrophilic, lid

packaging

pkg of 10 plates

manufacturer/tradename

MultiScreen®

technique(s)

DNA purification: suitable, activity assay: suitable (with precipitations), ligand binding assay: suitable, parallel artificial membrane permeation assay (PAMPA): suitable, receptor binding assay: suitable

plate size

96 wells

well maximum volume

300 μL

working volume

50-250 μL

pore size

0.45 μm pore size

application(s)

sample preparation

compatibility

manifold only

shipped in

ambient

storage temp.

no temp limit

General description

Filter Code: PCF
Increasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.

Application

Research Category
Assays

Protein

Physical form

Color Code: Clear

Other Notes

Automation Compatible: No

Legal Information

MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

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