G1001
D-Glutamic acid
≥99% (TLC), suitable for ligand binding assays
Synonym(s):
(R)-2-Aminoglutaric acid, (R)-2-Aminopentanedioic acid, D-Glu, R-(−)-1-Aminopropane-1,3-dicarboxylic acid
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About This Item
Linear Formula:
HO2CCH2CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
147.13
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
230-000-8
MDL number:
Beilstein/REAXYS Number:
1723800
Product Name
D-Glutamic acid, ≥99% (TLC)
Quality Level
assay
≥99% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
mp
200-202 °C (subl.) (lit.)
SMILES string
N[C@H](CCC(O)=O)C(O)=O
InChI
1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChI key
WHUUTDBJXJRKMK-GSVOUGTGSA-N
Gene Information
human ... CCR2(1231)
General description
D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan.
Application
D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors.
Biochem/physiol Actions
Unnatural isomer of glutamic acid.
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Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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