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Merck

P4957

Poly-ʟ-Ornithine

synthetic, mol wt 30,000-70,000, liquid, 0.01%, suitable for cell culture

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About This Item

CAS Number:
27378-49-0
UNSPSC Code:
12352202
PubChem Substance ID:
24898574
NACRES:
NA.75
MDL number:
MFCD00286305
Biological source:
synthetic
Form:
solution
Technique(s):
cell culture | mammalian: suitable
Concentration:
0.01%
Mol wt:
30,000-70,000

Key Documents

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Product Name

Poly-L-ornithine solution, mol wt 30,000-70,000, 0.01%, sterile-filtered, BioReagent, suitable for cell culture

SMILES string

Br.NCCCC(N)C(O)=O

InChI key

GWRQMKDBBHFVIZ-UHFFFAOYSA-N

InChI

1S/C5H12N2O2.BrH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H

biological source

synthetic

sterility

sterile-filtered

product line

BioReagent

form

solution

mol wt

30,000-70,000

packaging

pkg of 50 mL

concentration

0.01%

technique(s)

cell culture | mammalian: suitable

surface coverage

4 μg/cm2

impurities

endotoxin, tested

shipped in

ambient

storage temp.

2-8°C

Quality Level

200

Related Categories

General description

Poly-L-ornithine is a positively charged synthetic amino acid polymer.

Application

Poly-L-ornithine solution has been used in the induction of differentiation.
Poly-L-ornithine has been used successfully for the attachement and study of neural cell differentiation and outgrowth. Recommended as a cell culture substratum when using 0.5 ml of a 0.1 mg/ml solution to coat 25 cm2.

Biochem/physiol Actions

Poly-L-ornithine helps to improve the penetration of substances into cells. It can induce the uptake of DNA.

Preparation Note

Prepared in cell culture grade water.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
RNBL9395
RNBL6953
RNBL5426
RNBL4181
RNBL4699

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Plant Protoplasts: International Review of Cytology (2013)
Interferon (2009)
Ewoud B Compeer et al.
Nature communications, 9(1), 1597-1597 (2018-04-25)
Endocytosis of surface receptors and their polarized recycling back to the plasma membrane are central to many cellular processes, such as cell migration, cytokinesis, basolateral polarity of epithelial cells and T cell activation. Little is known about the mechanisms that
Differential effect of activin on mouse embryonic stem cell differentiation in insulin?secreting cells under nestin?positive selection and spontaneous differentiation protocols.
Jafary H, et al.
Cell Biology International, 32(2), 278-286 (2008)
Areechun Sotthibundhu et al.
EXCLI journal, 15, 829-841 (2017-03-10)
Melatonin, secreted mainly by the pineal gland, plays roles in various physiological functions including protecting cell death. We showed in previous study that the proliferation and differentiation of precursor cells from the adult mouse subventricular zone (SVZ) can be modulated
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