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32091

Sulfamonomethoxine

VETRANAL®, analytical standard

Synonym(s):

4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide, 4-Methoxy-6-sulfanilamidopyrimidine, N1-(6-Methoxy-4-pyrimidinyl)sulfanilamide, SMM

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O3S
CAS Number:
1220-83-3
Molecular Weight:
280.30
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329753732
MDL number:
MFCD00063466
Beilstein/REAXYS Number:
621128
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grade

analytical standard

Quality Segment

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

impurities

≤3.0% water

application(s)

clinical testing

format

neat

SMILES string

COc1cc(NS(=O)(=O)c2ccc(N)cc2)ncn1

InChI

1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)

InChI key

WMPXPUYPYQKQCX-UHFFFAOYSA-N

General description

Sulfamonomethoxine is classified under the sulfonamide group of compounds.
Chemical structure: sulfonamide

Application

Sulfamonomethoxine may be used as an analytical reference standard for the determination of sulfamonomethoxine in:
  • Tissues, milk and eggs of food-producing animals by ultrasound-assisted extraction (UAE) and liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
  • Food samples of animal origin by QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction procedure, SOSLE (salting-out supported liquid extraction) method and nanoflow liquid chromatography high resolution mass spectrometry (LC-HRMS).
  • Bovine muscles by hydrophilic interaction liquid chromatography (HILIC) combined with LC-MS/MS.
  • Commercial eggs by liquid-liquid extraction (LLE), hybrid solid-phase extraction (SPE) and LC-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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Analysis of trace levels of sulfonamides in fish tissue using micro-scale pipette tip-matrix solid-phase dispersion and fast liquid chromatography tandem mass spectrometry.
Shen Q, et al.
Food Chemistry, 194, 508-515 (2016)
Caixia Jin et al.
Ecotoxicology (London, England), 18(7), 878-885 (2009-06-26)
Investigation of the toxic effects of three veterinary drugs [sulfadiazine sodium (SDS), sulfamonomethoxine sodium (SMMS), and enrofloxacin (EFLX)] on seed germination, root elongation and shoot elongation of wheat (Triticum aestivum L.), Chinese cabbage (Brassica campestris L.) and tomato (Cyphomandra betacea)
Jingchun Yan et al.
Chemosphere, 87(2), 111-117 (2011-12-24)
Ferrous hydroxide colloids were prepared and characterized as an activator of H(2)O(2) for decomposing organic pollutants, such as Rhodamine B, sulfamonomethoxine (SMM) and 4-nitrophenol (4-NP). As major reactive oxygen species, hydroxyl radicals were confirmed to be generated in the activation
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