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Merck

146064

β-Alanine

99%, suitable for ligand binding assays

Synonym(s):

β-Ala, 3-Aminopropionic acid

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About This Item

Linear Formula:
NH2CH2CH2COOH
CAS Number:
Molecular Weight:
89.09
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
39030936
UNSPSC Code:
12352209
EC Number:
203-536-5
MDL number:
Beilstein/REAXYS Number:
906793
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Product Name

β-Alanine, 99%

Quality Level

assay

99%

form

powder, crystals or granules

technique(s)

ligand binding assay: suitable

color

white

mp

202 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

InChI key

UCMIRNVEIXFBKS-UHFFFAOYSA-N

Application

β-Alanine has been used as a ligand for the orphan MAS-related receptor. It has also been used in culture media used for certain strains of yeast to test for β-alanine auxotrophy.

Biochem/physiol Actions

Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine is a component of pantothenic acid.
β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.


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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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